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TranscriptomicsGene expression profiling of MDA231 cells with alterations involving beta-oxidation pathway
In order to confirm the role of fatty acid β-oxidation in Src regulation, we performed gene expression analysis in MDA231 cells from in vivo model treated with ETX or knockdown of CPT1 or CPT2 using shRNA. As expected, inhibition of β-oxidation showed a gene expression pattern that is opposite to ...
ORGANISM(S): Homo sapiens 
2016-04-14 | E-GEOD-72320 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of transmitochondrial cybrids (triple negative breast cancer cells in SUM159 background)
We used a transmitochondrial cybrid (cybrids)-based discovery approach to identify mitochondria-regulated cancer pathways in TN BCa. Cybrids were generated under a moderately metastatic TN BCa cell line SUM159 as the common nuclear background with mitochondria from benign breast epithelium (A1N4) an...
ORGANISM(S): Homo sapiens 
2016-04-14 | E-GEOD-72319 | biostudies-arrayexpress
ProteomicsFecal protein changes in different colorectal diseases
We examined fecal proteins from normal subjects (n=6), patients with inflammatory bowel disease (n=8), patients with colorectal adenoma (n=8), and patients with colorectal cancer (n=14) in the hope of identifying novel fecal protein markers that could be used to identify colorectal diseases.
ORGANISM(S): Homo Sapiens 
2022-12-22 | PXD039089 |
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