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Parkinson disease (PD) is the second most common age-related neurodegenerative disorder, which is related to neurotransmitter secretion impartment and the dysfunction of vesicle transport. Secretory granules (SGs) are a class of intracellular vesicles different from synaptic vesicles (SVs) in neuron...
ORGANISM(S): Homo sapiens (Human) 
2021-08-26 | PXD023937 | Pride
We used RNA-seq platform to determine role of a splicing factor RBM25 in regulation of gene expression and pre-mRNA splicing. We found that a loss-of-function allele of RBM25, rbm25-1, causes up- and down-regulation of a large number of genes. We further found that the rbm25-1 mutation results in d...
ORGANISM(S): Arabidopsis thaliana 
Klebsiella pneumoniae is an important opportunistic pathogen associated with multidrug-resistant infections in humans and animals. In this study, we performed a global proteomic analysis of the isolate JX21CTR26 to characterize its whole-cell protein expression profile. Bacterial cells were cultured...
ORGANISM(S): Klebsiella pneumoniae subsp. pneumoniae KpQ3 
2026-01-11 | PXD071946 | Pride
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