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UnknownHDAC1 disrupts the tricarboxylic acid (TCA) cycle through the deacetylation of Nur77 and promotes inflammation in ischemia-reperfusion mice.
Not available
S-EPMC9849262 | biostudies-literature
GenomicsGemone-wide maps of PRC2 complex components and chromatin states in prostate cancer cell lines
We report the high-throughput profiling of PRC2 core subunits chromatin states and histone modifications in two prostate cancer cell lines, androgen-dependent cells LNCaP and androgen-independent cells LNCaP-abl (abl). By obtaining over 1 billion bases of sequence from chromatin immunoprecipitated D...
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-39459 | biostudies-arrayexpress
TranscriptomicsExpression data of EZH2-dependent genes in prostate cancer cell lines
EZH2 is frequently over-expressed in aggressive and metastatic solid tumors, including castration resistant prostate cancer (CRPC). We sought to determine EZH2-dependent gene expression programmes in prostate cancer progression, and found an intriguing functional switch of EZH2 from a repressor to a...
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-39452 | biostudies-arrayexpress
UnknownGefitinib metabolism-related lncRNAs for the prediction of prognosis, tumor microenvironment and drug sensitivity in lung adenocarcinoma.
Not available
S-EPMC11074108 | biostudies-literature
UnknownEffect of adjuvants on physicochemical properties of lime sulfur on flower/paraffin and application on flower thinning.
Not available
S-EPMC10536241 | biostudies-literature
TranscriptomicsGene expression analysis of breast cancer cell-lines
Recurrent mutations in histone modifying enzymes in multiple cancer types imply key roles in tumorigenesis. However, the functional relevance of these mutations remains unknown. Here we show that the JARID1B histone H3 lysine 4 demethylase is frequently amplified and overexpressed in luminal breast ...
ORGANISM(S): Homo sapiens 
2014-06-17 | E-GEOD-45732 | biostudies-arrayexpress
GenomicsGenome-wide location analysis in breast cancer cell-lines
Recurrent mutations in histone modifying enzymes in multiple cancer types imply key roles in tumorigenesis. However, the functional relevance of these mutations remains unknown. Here we show that the JARID1B histone H3 lysine 4 demethylase is frequently amplified and overexpressed in luminal breast ...
ORGANISM(S): Homo sapiens 
2014-06-17 | E-GEOD-46055 | biostudies-arrayexpress
TranscriptomicsAltered antisense-to-sense transcript ratios in breast cancer: Agilent
Transcriptome profiling studies suggest that a large fraction of the genome is transcribed and many transcripts function independent of their protein coding potential. The relevance of noncoding RNAs (ncRNAs) in normal physiological processes and in tumorigenesis is increasingly recognized. Here, we...
ORGANISM(S): Homo sapiens 
2010-12-10 | E-GEOD-26000 | biostudies-arrayexpress
TranscriptomicsAltered antisense-to-sense transcript ratios in breast cancer: ASSAGE
Transcriptome profiling studies suggest that a large fraction of the genome is transcribed and many transcripts function independent of their protein coding potential. The relevance of noncoding RNAs (ncRNAs) in normal physiological processes and in tumorigenesis is increasingly recognized. Here, we...
ORGANISM(S): Homo sapiens 
2010-12-10 | E-GEOD-25932 | biostudies-arrayexpress
UnknownImpact of multimorbidity on health-related quality of life: the mediation role of intrinsic capacity - evidence from the WHO ICOPE pilot program in Lianyungang of China (2024).
Not available
S-EPMC12709750 | biostudies-literature
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