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With the advent of the induced pluripotent stem cell (iPSC) technology, how to distinguish the developmental potentials of the iPSC clones with molecular approaches becomes an imperative issue. Herein, we demonstrated that histone variant H2A.X plays an unexpected role in distinguishing the develop...
ORGANISM(S): Mus musculus 
It is well-known that embryonic stem cells (ESC) are much more sensitive to replication-induced stress than differentiated cells but the underpinning mechanisms are largely unknown. H2A.X, a minor variant of H2A, constitutes only 1-10% of the mammalian genome. H2A.X plays a well-known for role in t...
ORGANISM(S): Mus musculus 
Overexpression of Oxysterol-Binding Protein-Related Protein 3 (ORP3) in colorectal cancer cell lines
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD074308 | Pride
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
Collect proteomic data for organoids from relapsed neuroblastoma patients
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051208 | Pride
High-temperature stress (HTS) is one of the main environmental stresses that limit plant growth and crop production in agricultural systems. Maca (Lepidium meyenii) is an important high-altitude herbaceous plant adapted to a wide range of environmental stimuli such as cold, strong wind and UV-B expo...
ORGANISM(S): Lepidium meyenii 
2020-08-25 | PXD021042 | Pride
Herein, we demonstrated that the cell lineage commitment is unexpectedly regulated by the novel functions of H2A.X, a histone variant which was only well-known for its role in genome integrity maintenance previously. Surprisingly, only in ESCs but not differentiated cells, H2A.X is specifically targ...
ORGANISM(S): Mus musculus 
We collected a total of 9.8 million mass spectra data generated in the laboratory from the proteomics analyses of different silkworm tissues.
ORGANISM(S): Bombyx mori (Silk moth) 
2019-07-01 | PXD010096 | Pride
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