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TranscriptomicsIntegrative phenotypic and transcriptomic validation of an alveolar-like macrophage model reveals early host–pathogen dynamics during Aspergillus fumigatus infection
The saprophytic mold Aspergillus fumigatus produces small (2-3 µm) airborne spores (conidia) that can reach the lung alveoli upon inhalation. There, they encounter the surfactant-rich environment of the alveolar epithelium and initiate swelling and germination. Primary alveolar macrophages are essen...
ORGANISM(S): Homo sapiens 
2026-10-02 | E-MTAB-17130 | biostudies-arrayexpress
UnknownStreptozotocin-induced hyperglycemia alters the cecal metabolome and exacerbates antibiotic-induced dysbiosis.
Not available
S-EPMC8722030 | biostudies-literature
TranscriptomicsTranscription profiling of mouse embyronic fibroblasts from wild type and Lin9 knockout strains treated with 4-hydroxytestosterone
We used microarrays to analyze the role of Lin9 in gene expression. Experimental overall design: We prepared MEFs from embyos containing a conditional allele of Lin9 and a CreERT2 transgene. Transcriptional profiles of untreated and 4-OHT-treated MEFs were compared.
ORGANISM(S): Mus musculus 
2010-03-31 | E-MEXP-2097 | biostudies-arrayexpress
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