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GenomicsYAP1 and WWTR1 are required for murine pregnancy initiation
YAP1 and WWTR1 are required for murine pregnancy initiation
PRJNA1112897 | ENA
TranscriptomicsIdentification of Resistance Genes to BRAF Inhibitor in Melanoma by piggyBac Transposon Activation Mutagenesis Screen
Genotype directed anti-cancer therapies such BRAF inhibitor in BRAF mutant melanoma can show remarkable clinical efficacy but resistance limits their benefit. We show that a transposon activation screen efficiently identifies resistance genes to BRAF and captures a number of previously uncharacteriz...
ORGANISM(S): Homo sapiens 
2016-07-01 | E-GEOD-73470 | biostudies-arrayexpress
GenomicsEffect of PAX3-WWTR1 knockdown in rhabdomyosarcoma derived tumoroids
Effect of PAX3-WWTR1 knockdown in rhabdomyosarcoma derived tumoroids
PRJEB71929 | ENA
GenomicsRNA-Seq of rat cardiac fibroblasts depleted for Yap and Wwtr1
RNA-Seq of rat cardiac fibroblasts depleted for Yap and Wwtr1
PRJNA768827 | ENA
ProteomicsTAZ (WWTR1) Interactome Analysis using a GBP nanotrap based affinity purification approach
The transcriptional co-activator TAZ (WWTR1) plays a crucial role in regulating gene expression related to cell proliferation, differentiation, and tissue homeostasis, particularly within the Hippo signaling pathway. Since TAZ does not directly bind to DNA, it largely relies on its protein-protein i...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2025-02-11 | PXD060532 | Pride
Mass spectrometry Affinity-purification Skeletal muscle Taz Nanobody 
GenomicsRNA-seq of injured mouse hearts depleted for myofibroblast Yap and Wwtr1
RNA-seq of injured mouse hearts depleted for myofibroblast Yap and Wwtr1
PRJNA686945 | ENA
GenomicsInducible smooth muscle specific deletion of Yap1/Wwtr1 in mouse
Inducible smooth muscle specific deletion of Yap1/Wwtr1 in mouse
PRJNA632892 | ENA
TranscriptomicsMultiple roles for Wwtr1 in cardiac wall maturation
Cardiac trabeculation is a highly regulated process that starts with the delamination of cardiomyocytes from the compact wall to form stereotypical muscular ridges in the developing ventricle.  The Hippo signaling pathway has been implicated in cardiac development but many questions remain.  We inve...
ORGANISM(S): Danio rerio 
2018-04-10 | GSE103169 | GEO
UnknownGlomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.
Not available
S-EPMC1785239 | biostudies-literature
UnknownMice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs' Endothelial Corneal Dystrophy.
Not available
S-EPMC10132321 | biostudies-literature
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