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ProteomicsXenogeneic-free culture of human intestinal stem cells on functional polymer-coated substrates for scalable, clinical-grade stem cell therapy
Inevitable need for basement membrane extract (BME) with undefined constituents, such as Matrigel, for intestinal stem cell (ISC) culture in traditional system poses a significant barrier that must be overcome for the development of clinical-grade, scalable, ready-to-use ISCs. Here, we propose a fun...
ORGANISM(S): Homo sapiens (Human) 
2024-10-22 | PXD050747 | Pride
Intestinal tissue repair Intestinal stem cell derived from 3d human intestinal organoids (isc3d-hio) Stock banking system Xenogeneic-free culture Functional polymer coating 
ProteomicsXenogeneic-free culture of human intestinal stem cells on functional polymer-coated substrates for scalable, clinical-grade stem cell therapy
Inevitable need for basement membrane extract (BME) with undefined constituents, such as Matrigel, for intestinal stem cell (ISC) culture in traditional system poses a significant barrier that must be overcome for the development of clinical-grade, scalable, ready-to-use ISCs. Here, we propose a fun...
ORGANISM(S): Homo sapiens (Human) 
2025-07-07 | PXD050675 | Pride
Intestinal tissue repair Intestinal stem cell derived from 3d human intestinal organoids (isc3d-hio) Stock banking system Xenogeneic-free culture Functional polymer coating 
GenomicsXenogeneic-free culture of human intestinal stem cells on functional polymer-coated substrates for scalable, clinical-grade stem cell therapy
Xenogeneic-free culture of human intestinal stem cells on functional polymer-coated substrates for scalable, clinical-grade stem cell therapy
PRJNA1088872 | ENA
ProteomicsTailoring Polymer Surface for Long-term Reliable Xenogeneic-free Culture of Intestinal Stem Cells via Regulated Dynamic Migratory Behavior
Regenerative therapy employing intestinal stem cells (ISCs) holds a great promise for reliable epithelial restoration. However, achieving this goal requires scalable and robust, but fully defined culture platforms that eliminate the use of xenogeneic components while preserving stem cell function. M...
ORGANISM(S): Homo sapiens (Human) 
2025-07-07 | PXD064449 | Pride
Biomaterials Intestinal stem cells Plasma-treated polymers Cytoskeletal dynamics Surface engineering Regenerative medicine 
TranscriptomicsXenogeneic-free culture of human intestinal stem cells on functional polymer-coated substrates for scalable, clinical-grade stem cell therapy
Inevitable need for basement membrane extract (BME) with undefined constituents, such as Matrigel, for intestinal stem cell (ISC) culture in traditional system poses a significant barrier that must be overcome for the development of clinical-grade, scalable, ready-to-use ISCs. Here, we propose a fun...
ORGANISM(S): Homo sapiens 
2024-10-21 | GSE261785 | GEO
GenomicsHuman corneal endothelial cell cultures obtained from discarded tissues using a xenogeneic free culture medium
Human corneal endothelial cell cultures obtained from discarded tissues using a xenogeneic free culture medium
PRJNA949963 | ENA
UnknownChemically defined and xenogeneic-free differentiation of human pluripotent stem cells into definitive endoderm in 3D culture.
Not available
S-EPMC6353891 | biostudies-literature
UnknownEstablishment of xenogeneic serum-free culture methods for handling human dental pulp stem cells using clinically oriented in-vitro and in-vivo conditions.
Not available
S-EPMC5797401 | biostudies-literature
UnknownXenogeneic-free culture of human intestinal stem cells on functional polymer-coated substrates for scalable, clinical-grade stem cell therapy.
Not available
S-EPMC11612142 | biostudies-literature
UnknownA xenogeneic-free system generating functional human gut organoids from pluripotent stem cells.
Not available
S-EPMC5214546 | biostudies-literature
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