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TranscriptomicsTranscription profiling of human melanoma xenotransplant metastatis model - gene signature for aggression of melanoma metastases
Metastasis is the deadliest phase of cancer progression. Experimental models using immunodeficient mice have been used to gain insights into the mechanisms of metastasis. We report here the identification of a “metastasis aggressiveness gene expression signature” derived using human melanoma cel...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8401 | biostudies-arrayexpress
UnknownPatients' Information Needs for Informed Consent to Participate in First-in-Human Pig Kidney Xenotransplant Clinical Trials: A Mixed Methods Study.
Not available
S-EPMC11851052 | biostudies-literature
UnknownTransplant Patients' Perceptions About Participating in First-in-Human Pig Kidney Xenotransplant Clinical Trials: A Mixed Methods Study.
Not available
S-EPMC11800742 | biostudies-literature
GenomicsSpatiotemporal immune atlas of a clinical-grade gene-edited pig-to-human kidney xenotransplant
Spatiotemporal immune atlas of a clinical-grade gene-edited pig-to-human kidney xenotransplant
PRJNA1012812 | ENA
UnknownA data-driven analysis of patient selection for xenotransplant human clinical trials.
Not available
S-EPMC12668613 | biostudies-literature
TranscriptomicsP493-6 treated with KJ-Pyr-9 and/or Doxycycline
In a fluorescence polarization screen for MYC-MAX interaction, we have identified a novel small molecule inhibitor of MYC, KJ-Pyr-9, from a Kröhnke pyridine library. The Kd of KJ-Pyr-9 for MYC in vitro is 6.5 ± 1.0 nM as determined by backscattering interferometry; KJ-Pyr-9 also interferes with MYC-...
ORGANISM(S): Homo sapiens 
2014-08-25 | E-GEOD-58168 | biostudies-arrayexpress
UnknownStimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer.
Not available
S-EPMC3287235 | biostudies-literature
UnknownA zebrafish xenotransplant model of anaplastic thyroid cancer to study the tumor microenvironment and innate immune cell interactions in vivo.
Not available
S-EPMC10312444 | biostudies-literature
TranscriptomicsSOX11-positive and SOX11-knockdown xenograft derived tumor Gene Expression Profilings
The neural transcription factor SOX11 is overexpressed in aggressive lymphoid neoplasms mainly in mantle cell lymphoma (MCL). We have recently demonstrated SOX11 tumorigenic potential in vivo by showing a significant reduction on tumor growth of SOX11-knockdown MCL cells in xenograft experiments, co...
ORGANISM(S): Homo sapiens 
2014-11-04 | E-GEOD-52892 | biostudies-arrayexpress
UnknownNormal Graft Function After Pig-to-Human Kidney Xenotransplant.
Not available
S-EPMC10433134 | biostudies-literature
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