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TranscriptomicsTrans-splicing in human embryonic stem cells
Trans-spliced isoform of NCRMS (tsNCRMS) tends to be specifically transcribed in hESCs/iPSCs and disruption of tsNCRMS expression can conspicuously affect the pluripotency maintenance of hESCs. We disrupt the expression of tsNCRMS by introducing tsNCRMS shTS2 that target the no-co-linear junction si...
ORGANISM(S): Homo sapiens 
2013-09-30 | E-GEOD-32503 | biostudies-arrayexpress
TranscriptomicsmiR-200c is Aberrantly Expressed in Leiomyomas in Ethnic-Dependent Manner and Targets ZEBs, VEGFA, TIMP2 and FBLN5
mircoRNA-200c (miR-200c) through repression of specific target genes has been associated with cellular transition, tumorigenesis and tissue fibrosis. We explored the expression and functional aspects of miR-200c in genesis of leiomyomas, benign uterine tumors with fibrotic characteristic. Gain-of fu...
ORGANISM(S): Homo sapiens 
2012-06-20 | E-GEOD-38817 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human cancer cells after treatment with the chromatin modifying drugs 5-aza-2 deoxycytidine and 4-phenylbutyric acid
miRNA expression profiling in human cancer cells after 5-aza-2'-deoxycytidine and 4-phenylbutyric acid treatment to investigate whether microRNA expression is controlled by these chromatin modifying drugs.
ORGANISM(S): Homo sapiens 
2005-01-01 | E-MEXP-706 | biostudies-arrayexpress
UnknownConjugated linoleic acid reduces adiposity and increases markers of browning and inflammation in white adipose tissue of mice.
Not available
S-EPMC3605998 | biostudies-literature
UnknownSigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope.
Not available
S-EPMC4664336 | biostudies-literature
UnknownPrevalence and risk factors of training-related abdominal injuries: A multicenter survey study.
Not available
S-EPMC12281937 | biostudies-literature
TranscriptomicsRadiation-Induced Changes in Gene Expression Involve Recruitment of Existing Messenger RNAs to and from Polysomes
Although ionizing radiation has been shown to influence gene transcription, little is known about the effects of radiation on gene translational efficiency. To obtain a genome-wide perspective of the effects of radiation on gene translation, microarray analysis was done on polysome-bound RNA isolate...
ORGANISM(S): Homo sapiens 
2008-05-21 | E-GEOD-11517 | biostudies-arrayexpress
TranscriptomicsGlobal analysis of non-co-linear transcripts in human embryonic stem cells
We investigate different types of non-co-linear RNA, for example, circular, trans-splicing and gene fusion. Human (H9) and Rhesus macaque (O6) RNA-seqs
ORGANISM(S): Macaca mulatta 
2016-02-16 | E-GEOD-77920 | biostudies-arrayexpress
TranscriptomicsAntiangiogenic Antithrombin
Confluent passage-2 HUVECs in Falcon T12.5 flasks grown in the presence or absence of VEGF-165 (10ng/mL) (R&D systems) were treated with human native, cleaved or latent antithrombins (20 5g/mL) for 24 hours in 3 mL M-199 with 2% heat-inactivated FBS and antibiotics. Following this treatment, tot...
ORGANISM(S): Homo sapiens 
2005-12-30 | E-GEOD-3956 | biostudies-arrayexpress
TranscriptomicsmiR-93/106b and their host gene, MCM7, are differentially expressed in leiomyomas and functionally target F3 and IL-8
miR-93/106b and their host gene minichromosome maintenance complex component 7 (MCM7) reside at chr7q22, a region frequently rearranged in leiomyomas. We explored the expression of miR-93/106b in leiomyoma and paired myometrium (N=62) from untreated and patients exposed to hormonal therapies (GnRHa,...
ORGANISM(S): Homo sapiens 
2012-04-09 | E-GEOD-37122 | biostudies-arrayexpress
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