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UnknownEfficacy and safety of Ding-Kun-Dan for female infertility patients with predicted poor ovarian response undergoing in vitro fertilization/intracytoplasmic sperm injection: study protocol for a randomized controlled trial.
Not available
S-EPMC5819272 | biostudies-literature
GenomicsGenomic maps of lincRNA occupancy reveal principles of RNA-chromatin interactions.
Long intergenic noncoding RNAs (lincRNAs) are key regulators of chromatin state, yet the nature and sites of RNA-chromatin interaction are mostly unknown. Here we introduce Chromatin Isolation by RNA Purification (ChIRP), where tiling oligonucleotides retrieve specific lincRNAs and bound protein and...
ORGANISM(S): Drosophila 
2011-09-29 | E-GEOD-31332 | biostudies-arrayexpress
TranscriptomicsDynamic Chromatin Localization of Sirt6 Shapes Stress- and Aging- Related Transcriptional Networks
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2011-05-11 | E-GEOD-28641 | biostudies-arrayexpress
GenomicsA pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics
Pseudogenes are thought to be inactive gene sequences, but recent evidence of extensive pseudogene transcription raised the question of potential function. Here we discover and characterize the sets of lncRNAs induced by inflammatory signaling via TNFα. TNFα regulates hundreds of lncRNAs, including...
ORGANISM(S): Mus musculus 
2013-08-05 | E-GEOD-47494 | biostudies-arrayexpress
TranscriptomicsAn Ets2-specific transcriptional program in tumor-associated macrophages promotes metastasis
Macrophages have been implicated in breast cancer progression and metastasis, but relatively little is known about the genes and pathways that are involved. Using a conditional allele of Ets2 in the mouse, we have identified Ets2 as a critical gene in tumor associated macrophages (TAMs) that specif...
ORGANISM(S): Mus musculus 
2010-01-05 | E-GEOD-12863 | biostudies-arrayexpress
GenomicsGenome-wide survey of YY1 targets in C2C12 cells by High-throughput sequencing
By applying ChIP-seq, we generated genome-wide maps of YY1 in skeletal myoblasts and myotubes. We found that YY1 binds to 1820 confident target with a large portion residing in the intergenic regions. In addition, YY1 was found to activate many loci, and there is no significant overlap between YY1 a...
ORGANISM(S): Mus musculus 
2013-08-15 | E-GEOD-45875 | biostudies-arrayexpress
TranscriptomicsRecapitulation of human premature aging by using iPSCs from Hutchinson-Gilford progeria syndrome
Hutchinson-Gilford progeria syndrome (HGPS) is a rare and fatal human premature aging disease1-5, characterized by premature atherosclerosis and degeneration of vascular smooth muscle cells (SMCs)6-8. HGPS is caused by a single-point mutation in the LMNA gene, resulting in the generation of progerin...
ORGANISM(S): Homo sapiens 
2011-03-14 | E-GEOD-24487 | biostudies-arrayexpress
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