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ProteomicsSDH deficiency-driven succinate accumulation dictates the drug resistance of AML through regulating p-UBC12/cullin activity
Drug resistance is vital for the poor prognosis of acute myeloid leukemia (AML) patients, but the underlying mechanism remains poorly understood. Given the unique microenvironment of bone marrow, we reasoned that drug resistance of AML might rely on distinct microenvironment-associated metabolic pro...
ORGANISM(S): Homo sapiens (Human) 
2024-08-28 | PXD047175 | Pride
Sdh deficiency  succinate  drug resistance  ubc12 phosphorylation  acute myeloid leukemia. 
UnknownPhytochemical Profile and Antioxidant Activity of the Tuber and Peel of <i>Pachyrhizus erosus</i>.
Not available
S-EPMC12023986 | biostudies-literature
UnknownTricistronic hepatitis C virus subgenomic replicon expressing double transgenes.
Not available
S-EPMC4277965 | biostudies-literature
UnknownFibrillarin promotes homologous recombination repair by facilitating the recruitment of recombinase RAD51 to DNA damage sites.
Not available
S-EPMC10710916 | biostudies-literature
UnknownEvaluation of SAT-Candida: a rapid RNA-based isothermal amplification assay for detection and identification of Candida spp. in vaginal specimens.
Not available
S-EPMC12482817 | biostudies-literature
UnknownEvaluating the quality of life among melasma patients using the MELASQoL scale: A systematic review and meta-analysis.
Not available
S-EPMC8794204 | biostudies-literature
UnknownExplainable machine learning models for predicting of protein-energy wasting in patients on maintenance haemodialysis.
Not available
S-EPMC12523148 | biostudies-literature
UnknownNovel and novel de novo mutations in NTRK1 associated with congenital insensitivity to pain with anhidrosis: a case report.
Not available
S-EPMC4602583 | biostudies-literature
UnknownNerve growth factor (NGF) with hypoxia response elements loaded by adeno-associated virus (AAV) combined with neural stem cells improve the spinal cord injury recovery.
Not available
S-EPMC8531363 | biostudies-literature
ProteomicsTMT-based quantitative proteomic analysis of serum from patients with postherpetic neuralgia reveals a key role of Endoglin in neuropathic pain via TGF-β/Smad2 signaling
This dataset comprises a Tandem Mass Tag (TMT)-based quantitative proteomic analysis of serum samples from patients with postherpetic neuralgia (PHN) compared to healthy control subjects. The study aimed to identify differentially expressed proteins involved in the pathogenesis of neuropathic pain. ...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD067890 | Pride
Quantitative proteomics Endoglin (cd105) Neuropathic pain Tandem mass tag (tmt) Tgf-β/smad2 signaling Ostherpetic neuralgia (phn) Biomarker Blood-spinal cord barrier (bscb) 
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