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ProteomicsGu-Ben-Fang-Xiao decoction ameliorates airway remodeling by regulating the PI3K/AKT signaling pathway mediated by RTN4 in a chronic remission asthma murine model
Airway remodeling is a main pathological feature of asthma. The current therapy for asthma is mainly targeted for reducing inflammation, not particularly for airway remodeling. Herein, developing alternative and more effective therapy to attenuate remodeling is worthy of further study. Gu-Ben-Fang-X...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD020711 | Pride
Rtn4 Pi3k/akt pathway Gu-ben-fang-xiao decoction Chronic remission asthma Airway remodeling 
UnknownRedetermination and absolute configuration of (+)-7-epiclusianone.
Not available
S-EPMC3515307 | biostudies-literature
TranscriptomicsIdentification of a stable molecular signature in breast tumor endothelial cells that persists ex vivo
Long-term, in vitro propagation of tumor-specific endothelial cells (TEC) allows for ex vivo functional studies and gene expression profiling of clonally-derived, well-characterized subpopulations. Using a genetically-engineered mouse model (GEMM) of mammary adenocarcinoma (C3-TAg), we have optimize...
ORGANISM(S): Mus musculus 
2014-03-21 | E-GEOD-50555 | biostudies-arrayexpress
ProteomicsThe NuRD complex is required for Thpok-mediated CD4+ T cell development
This data represent characterization of the interactome of murine Thpok. A version of Thpok (Thpok-Bio) subject to biotinylation in vivo by the BirA biotin ligase was used; to assess Thpok interactions in primary cells, Thpok-Bio was retrovirally expressed in in vitro activated CD4+ T cells from Thp...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
MSV000088126 | MassIVE
UnknownHuman papillomavirus and rising oropharyngeal cancer incidence in the United States.
Not available
S-EPMC3221528 | biostudies-literature
TranscriptomicsMapping genetic modifiers of ARPKD
Autosomal recessive polycystic kidney disease (ARPKD) is caused by mutations in the PKHD1 gene in both humans and the orthologous PCK rat model. Although ARPKD results solely from PKHD1 mutations, the disease onset and severity are highly variable, indicating that other unknown genetic risk factor(s...
ORGANISM(S): Rattus norvegicus 
2015-06-06 | E-GEOD-58229 | biostudies-arrayexpress
UnknownInhibitory Interactions and Columnar Inputs to an Object Motion Detector in Drosophila.
Not available
S-EPMC7210872 | biostudies-literature
UnknownFibroblast growth factor-2 isoform (low molecular weight/18 kDa) overexpression in preosteoblast cells promotes bone regeneration in critical size calvarial defects in male mice.
Not available
S-EPMC3929728 | biostudies-literature
UnknownSeasonal Fluctuations in Nitrate Levels Can Trigger Lead Solder Corrosion Problems in Drinking Water.
Not available
S-EPMC9835880 | biostudies-literature
UnknownGeometric preferences in iron(II) and zinc(II) model complexes of peptide deformylase.
Not available
S-EPMC2760226 | biostudies-literature
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