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TranscriptomicsLarge airway epithelial cells from cigarette smokers with and without lung cancer undergoing flexible bronchoscopy in the operating room for resection of a suspicious lung nodule
mRNA expression was assayed from bronchial epithelial cell samples from smokers with and without lung cancer. A subset of the samples (2 of the lung cancer samples and 3 of the no cancer samples) were pooled and underwent whole transcriptome sequencing. The goals were to compare whole transcriptom...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-28835 | biostudies-arrayexpress
TranscriptomicsmRNA-seq of Human Airway Epithelial Cells
mRNA expression was profiled from pooled bronchial airway epithelial cell brushings (n=3 patients/pool) obtained during bronchoscopy from healthy never (NS) and current smokers (S) and smokers with (C) and without (NC) lung cancer 4 samples were sequened, each representing a pool of 3 patients. The...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-29006 | biostudies-arrayexpress
TranscriptomicsCharacterization of an Oxaliplatin Sensitivity Predictor in a preclinical Murine Model of Colorectal Cancer
Despite advances in contemporary chemotherapeutic strategies, long term survival still remains elusive for patients with metastatic colorectal cancer. A better understanding of the molecular markers of drug sensitivity to match therapy with patient is needed to improve clinical outcomes. In this stu...
ORGANISM(S): Homo sapiens 
2012-02-17 | E-GEOD-28691 | biostudies-arrayexpress
GenomicsPOPRES: Population Reference Sample

Technological and scientific advances, stemming in large part from the Human Genome and HapMap projects, have made large-scale, genome-wide investigations feasible and cost-effective. These advances have the potential to dramatically impact drug discovery and development by identifying genet...

phs000145.v2.p2 | EGA
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