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UnknownData for identification of porcine X-chromosome inactivation center, XIC, by genomic comparison with human and mouse XIC.
Not available
S-EPMC4689114 | biostudies-literature
UnknownEpigenetic-structural changes in X chromosomes promote Xic pairing during early differentiation of mouse embryonic stem cells.
Not available
S-EPMC9174021 | biostudies-literature
ProteomicsProtein accumulation post-LASIK surgery in granular corneal dystrophy type II patients involves altered proteolytic processing of transforming growth factor beta-induced protein (TGFBIp)
his study present the protein profile of diseased cornea from granular corneal dystrophy patients developing protein accumulation after LASIK surgery. Extracted ion chromatography (XIC) label free quantification was perform using Mascot Distiller software. In addition, 2D-PAGE followed by western bl...
ORGANISM(S): Homo sapiens (Human) 
2016-02-19 | PXD001997 | Pride
Cornea Tripletof 5600+ Xic quantification 2d-page Granular corneal dystrophy 
ProteomicsAn XIC-centric approach for improved identification and quantification in proteomic data analyses
An XIC-centric approach for improved identification and quantification in proteomic data analyses
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-01-16 | MSV000093875 | MassIVE
OtherPAR-TERRA RNA directs homologous sex chromosome pairing
In mammals, homologous chromosomes rarely pair outside meiosis. One exception is the X chromosome, which transiently pairs during X-chromosome inactivation (XCI). How two chromosomes find each other in 3D space is not known. Here, we reveal a required interaction between the X-inactivation center (X...
ORGANISM(S): Mus musculus 
2017-07-10 | GSE69887 | GEO
GenomicsHigh resolution analysis of epigenetic changes associated with X inactivation, ChIP-Seq
This study describes the epigenetic profiling of the X chromosome during X inactivation. It includes H3K4me3 and H3K27me3 ChIP-Seq profiles of male (E14) and female (LF2 and XT67E1) mouse ES cells, together with their differentiated derivatives (either 4d atRA or 10d EB). It also includes ChIP-chip ...
ORGANISM(S): Mus musculus 
2009-06-06 | E-GEOD-15814 | biostudies-arrayexpress
TranscriptomicsHigh resolution analysis of epigenetic changes associated with X inactivation, ChIP-chip
This study describes the epigenetic profiling of the X chromosome during X inactivation. It includes H3K4me3 and H3K27me3 ChIP-Seq profiles of male (E14) and female (LF2 and XT67E1) mouse ES cells, together with their differentiated derivatives (either 4d atRA or 10d EB). It also includes ChIP-chip ...
ORGANISM(S): Mus musculus 
2010-05-18 | E-GEOD-15883 | biostudies-arrayexpress
TranscriptomicsThe bipartite TAD organization of the X-inactivation centre ensures opposing developmental regulation of Tsix and Xist
The mouse X-inactivation center (Xic) locus represents a powerful model for understanding the links between genome architecture and gene regulation, with the non-coding genes Xist and Tsix showing opposite developmental expression patterns while being organized as an overlapping sense/antisense unit...
ORGANISM(S): Mus musculus 
2019-05-27 | GSE111205 | GEO
ProteomicsPeptide Filtering and Quantification Methods
In bottom-up proteomics, data are acquired on peptides resulting from proteolysis. In XIC-based quantification, the quality of the protein abundance estimation depends on how peptide data are filtered and on which quantification method is used to sum up peptide intensities into protein abundances. S...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2018-11-14 | PXD009740 | Pride
Peptide filtering Quantification methods Extracted ion current 
UnknownPAR-TERRA directs homologous sex chromosome pairing.
Not available
S-EPMC5553554 | biostudies-literature
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