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UnknownApplication of ex-vivo spheroid model system for the analysis of senescence and senolytic phenotypes in uterine leiomyoma.
Not available
S-EPMC6265265 | biostudies-literature
UnknownOxidative stress-induced miRNAs modulate AKT signaling and promote cellular senescence in uterine leiomyoma.
Not available
S-EPMC6135677 | biostudies-literature
ProteomicsLong noncoding RNA lnc-POP1-1 upregulated by VN1R5 promotes cisplatin resistance in head and neck squamous cell carcinoma through interaction with MCM5
Cisplatin resistance is a major therapeutic challenge in advanced head and neck squamous cell carcinoma (HNSCC). Here, we aimed to investigate the key signaling pathway for cisplatin resistance in HNSCC cells. HNSCC cell lines that were sensitive (HN4 and HN30) or resistant (HN4/DDP and HN30/DDP) to...
ORGANISM(S): Homo Sapiens 
2020-11-28 | PXD022799 |
ProteomicsLow-dose Cu exposure enhanced α-synuclein accumolation associates with mitochondtial impairments in mouse model of Parkinson's disease
Parkinson's disease (PD) is a neurodegenerative disorder that mainly affects the elder population, and its etiology is enigmatic. Both environmental risks and genetics may influence the development of PD. Excess copper causes neurotoxicity and accelerates the progression of neurodegenerative dise...
ORGANISM(S): Mus Musculus 
2023-02-09 | PXD039976 |
ProteomicsMass spectrum data for the manuscript "Mitochondriomics reveals the underlying neuoprotective mechanism of TrkB receptor agonist R13 in the 5xFAD mice"
This is the original mass spectrometry data, which includes 45 mass spectra data and a search database table. All these data and sample processing methods can refer to the ca in the manuscript
ORGANISM(S): Mus Musculus 
2021-02-19 | PXD024268 |
ProteomicsMulti-omics analysis of human peripheral blood reveals marked molecular profiling changes caused by one night of sleep deprivation
Sleep insufficiency is associated with various disorders (cardiovascular disease, neurodegenerative diseases, immunological disorders.) but the molecular bases for these associations are largely unknown. We used multiple omics techniques to examine changes in the blood of healthy male and female adu...
ORGANISM(S): Homo Sapiens 
2022-04-23 | PXD033402 |
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