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UnknownKv2.1 clusters on β-cell plasma membrane act as reservoirs that replenish pools of newcomer insulin granule through their interaction with syntaxin-3.
Not available
S-EPMC5936832 | biostudies-literature
TranscriptomicsNuclear orphan receptor TAK1/TR4-deficient mice are protected against obesity-linked inflammation, hepatic steatosis, and insulin resistance
The nuclear receptor TAK1/TR4/NR2C2 is expressed in several tissues that are important in the control of energy homeostasis. TAK1-deficient (TAK1-/-) mice are resistant to the development of age- and high fat diet (HFD)-induced metabolic syndrome. Biochemical analysis showed significantly lower hepa...
ORGANISM(S): Mus musculus 
2010-09-30 | E-GEOD-21903 | biostudies-arrayexpress
TranscriptomicsRequirement for flap endonuclease 1 (FEN1) to maintain genomic stability and transcriptional gene silencing in Arabidopsis
As a central component during Okazaki fragment maturation, flap endonuclease 1 (FEN1) removes the 5’ flap and maintains genomic stability. Here, FEN1 was cloned as a suppressor of transcriptional gene silencing (TGS) from a forward genetic screen. FEN1 is abundant in the root and shoot apical meri...
ORGANISM(S): Arabidopsis thaliana 
2016-05-28 | E-GEOD-79738 | biostudies-arrayexpress
TranscriptomicsNuclear receptor, RORa plays a critical role in obesity-associated inflammation, hepatic steatosis, and insulin resistance
We demonstrated that RORa-deficient staggerer mice (RORasg/sg) fed with a high fat diet (HFD) showed reduced adiposity and hepatic triglyceride levels compared to wild type (WT) littermates and were resistant to the development of hepatic steatosis, adipose-associated inflammation, and insulin resis...
ORGANISM(S): Mus musculus 
2011-04-30 | E-GEOD-23736 | biostudies-arrayexpress
UnknownKlebsiella grimontii, a New Species Acquired Carbapenem Resistance.
Not available
S-EPMC6142883 | biostudies-literature
UnknownEfficient Adsorption of Ammonia by Surface-Modified Activated Carbon Fiber Mesh.
Not available
S-EPMC10648919 | biostudies-literature
UnknownTranscriptome Analysis of Differentially Expressed Genes Induced by Low and High Potassium Levels Provides Insight into Fruit Sugar Metabolism of Pear.
Not available
S-EPMC5450510 | biostudies-literature
UnknownFabrication of PA-PEI-MOF303(Al) by Stepwise Impregnation Layer-by-Layer Growth for Highly Efficient Removal of Ammonia.
Not available
S-EPMC9964625 | biostudies-literature
UnknownATP modulates interaction of syntaxin-1A with sulfonylurea receptor 1 to regulate pancreatic beta-cell KATP channels.
Not available
S-EPMC3037700 | biostudies-literature
MetabolomicsPlasma metabolome alteration in dairy cows with left displaced abomasum before and after surgical correction
Left displaced abomasum (LDA) leads to substantial changes in the metabolism of dairy cows. Surgical correction of LDA can rapidly improve the health of cows; however, changes in metabolism following surgery are rarely described. To investigate the changes of plasma metabolome in cows with LDA befor...
2022-08-17 | MTBLS4126 | MetaboLights
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