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UnknownChinese giant salamander Bcl-w: An inhibitory role in iridovirus-induced mitochondrial apoptosis and virus replication.
Not available
S-EPMC10445403 | biostudies-literature
MetabolomicsHyocholic acid species as novel biomarkers for metabolic disorders
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
GenomicsTELP, a sensitive and versatile library construction method for next-generation sequencing
Next-generation sequencing has been widely used for the genome-wide profiling of histone modifications, transcription factor binding and gene expression through chromatin immunoprecipitated DNA sequencing (ChIP-seq) and cDNA sequencing (RNA-seq). Here, we describe a versatile library construction me...
ORGANISM(S): Mus musculus 
2015-12-15 | E-GEOD-75966 | biostudies-arrayexpress
UnknownFacile Transformation from Rofecoxib to a New Near-Infrared Lipid Droplet Fluorescent Probe and Its Investigations on AIE Property, Solvatochromism and Mechanochromism.
Not available
S-EPMC9967153 | biostudies-literature
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
MetabolomicsComparative characterization of the infant gut microbiome and their maternal lineage by a multi-omics approach

The human gut microbiome establishes and matures during infancy, and dysregulation at this stage may lead to pathologies later in life. We conducted a multi-omics study comprising three generations of family members to investigate the early development of the gut microbiota. Fecal samples from 20...

2024-03-07 | MTBLS7670 | MetaboLights
ProteomicsTranscription Factor Acj6 Specifies Distinct Dendrite Targets via Unique Cell-Surface Protein Combinations
Xie Q, Li J1, Li H, Udeshi ND, Svinkina T, Kohani S, Guajardo R, Mani DR, Xu C, Li T, Han S, Wei W, Shuster SA, Luginbuhl DJ, Ting AY, Carr SA, Luo L. 2022. Transcription factors specify the fate and connectivity of developing neurons. To understand how distal neurites execute commands from these nu...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2022-04-01 | MSV000089187 | MassIVE
TranscriptomicsThe role of FGF21 in aging and aging-related diseases
Aging and aging-related diseases represent an increasing burden on modern society. Thus, drugs that retard the aging process are highly desirable. Fibroblast growth factor-21 (FGF21) is a hormone secreted by the liver during fasting that elicits diverse aspects of the adaptive starvation response....
ORGANISM(S): Mus musculus 
2012-10-18 | E-GEOD-39313 | biostudies-arrayexpress
TranscriptomicsThe prognostic and predictive value of a six-microRNA-based classifier in stage II colon cancer
microRNA profiling of colon tumor tissues vs adjacent normal tissues 40 paired tumor and adjacent normal tissues of stage M-bM-^EM-! colon caner
ORGANISM(S): Homo sapiens 
2013-11-29 | E-GEOD-49246 | biostudies-arrayexpress
GenomicsHeterochromatin remodeling by CDK12 contributes to learning in Drosophila
We describe the epigenetic profiling of the H3K9me2 and HP1a in Drosophila third instar larvae before and after CDK12 depletion by RNA interference (RNAi). Here we show that CDK12 regulates heterochromatin dynamics in Drosophila chromosomes. Depletion of CDK12 induces the increased HP1a and H3K9me2 ...
ORGANISM(S): Drosophila melanogaster 
2015-11-02 | E-GEOD-63011 | biostudies-arrayexpress
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