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Gene expression profiling of the effets of marinobufagenin in a time-course study (0, 0.25, 0.5, 0.75, 1, 2, 3, 6, 9, 12, 15, and 24 hrs) to examine the temporal changes in gene expression in a human dermal fibroblast cell line. Keywords: Time course Cells were treated with 10 nM of marinobufagenin ...
ORGANISM(S): Homo sapiens 
Lithocholic acid (LCA), accumulated in mammals during calorie restriction (CR), can activate AMP-activated protein kinase (AMPK) and slow down ageing1. However, how LCA is signalled to activate AMPK and elicit the biological effects is unclear. Here, we show that LCA can enhance the activity of sirt...
ORGANISM(S): Homo Sapiens Mus Musculus 
2024-09-16 | PXD056134 |
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