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ANCA associated vasculitis(AAV) is a systemic vasculitis of small vessels, characterzied by injury of vascular endothelial cells induced by abnormally activated neutrophils. Microscopic polyangiitis (MPA) is a member of AAV with a high risk of kidney involvement. Blood lipid disorder promotes endoth...
ORGANISM(S): Homo sapiens (Human) 
2025-01-06 | PXD045969 | Pride
A total of 6081 proteins were identified in this study, of which 5267 proteins contained quantitative information. If taking 1.2 times as the change threshold and t-test p-value < 0.05 as the standard, the expression of 335 proteins in 92.1-a / 92.1 comparison group was up-regulated and 302 proteins...
ORGANISM(S): Homo sapiens (Human) 
2022-03-21 | PXD032215 | Pride
We describe the epigenetic profiling of the H3K9me2 and HP1a in Drosophila third instar larvae before and after CDK12 depletion by RNA interference (RNAi). Here we show that CDK12 regulates heterochromatin dynamics in Drosophila chromosomes. Depletion of CDK12 induces the increased HP1a and H3K9me2 ...
ORGANISM(S): Drosophila melanogaster 
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