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GenomicsCpG context and content in evolutionary signatures of brain DNA methylation
We assayed CpG methylation in cerebral cortex of neurologically and psychiatrically normal human postmortem specimens, as well as mouse forebrain specimens. Cross-species human-mouse DNA methylation conservation analysis shows that DNA methylation is not correlated with sequence conservation. Instea...
ORGANISM(S): Homo sapiens 
2011-10-04 | E-GEOD-32647 | biostudies-arrayexpress
TranscriptomicsUse of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells
This study provides an assessment of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells. The system combines microfluidic technology and nanoliter-scale reactions. We sequenced 622 cells allowing identification of 341 islet cells with high-quality gene expression prof...
ORGANISM(S): Mus musculus 
2016-02-19 | E-GEOD-77980 | biostudies-arrayexpress
MetabolomicsFecal Metabolomics and Potential Biomarkers for Systemic Lupus Erythematosus
The role of metabolomics in autoimmune diseases has been a rapidly expanding area in researches over the last decade, while its pathophysiologic impact on systemic lupus erythematosus (SLE) remains poorly elucidated. In this study, we analyzed the metabolic profiling of fecal samples from SLE patien...
2020-01-30 | MTBLS916 | MetaboLights
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