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UnknownSurgeon influence on use of needle biopsy in patients with breast cancer: a national medicare study.
Not available
S-EPMC4164811 | biostudies-literature
ProteomicsProteomics analysis on SETD2 deficient intestinal epithelial cells
SETD2 is a methyltransferase critical for the integrity of epithelial barrier. However, the role of SETD2 in safeguarding epithelial barrier integrity remains largely unexplored. Here, we performed proteomics analysis on intact intestinal barrier with SETD2 present and compromised intestinal barrier...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-04-06 | PXD055747 | Pride
Proteomics ip-ms 
ProteomicsPreferential phosphorylation on old histones during early mitosis in human cells
How histone posttranslational modifications (PTMs) are inherited through cell cycle remains poorly understood. Canonical histones are made in the S phase of cell cycle. Combining mass spectrometry-based technologies and stable isotope labeling by amino acids in cell culture (SILAC), we interrogate t...
ORGANISM(S): Homo sapiens (Human) 
2016-06-01 | PXD003709 | Pride
Mass spectrometry Mitosis Histone modifications Cell cycle Histone phosphorylation 
UnknownToxoplasma gondii immune mapped protein 1 is anchored to the inner leaflet of the plasma membrane and adopts a novel protein fold.
Not available
S-EPMC5716462 | biostudies-literature
UnknownPIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment.
Not available
S-EPMC5046836 | biostudies-literature
ProteomicsGuanine-containing ssDNA and RNA induce dimeric and tetrameric SAMHD1 in cryo-EM and binding studies
The dNTPase activity of tetrameric SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1) plays a critical role in cellular dNTP regulation. SAMHD1 also associates with stalled DNA replication forks, DNA repair foci, ssRNA, and telomeres. The above functions require...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2023-11-13 | PXD043587 | Pride
Aicardi-goutieres syndrome Dna repair Rnase Sammhd1 Hiv 
UnknownThe Role of Glycocalyx Diversity and Thickness for Nanoparticle Internalization in M1-/M2-like Macrophages.
Not available
S-EPMC11638944 | biostudies-literature
UnknownIntraperitoneal Pretargeted Radioimmunotherapy for Colorectal Peritoneal Carcinomatosis.
Not available
S-EPMC9157533 | biostudies-literature
MetabolomicsDietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Ferroptosis is mediated by lipid peroxidation of phospholipids containing polyunsaturated fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid peroxidation via the activity of the enzyme glutathione peroxidase 4 (GPX-4), is generated directly from the sulfur-...

2023-01-11 | MTBLS5959 | MetaboLights
ProteomicsSpatiotemporal Deciphering of Dynamic Proteome during Liquid-Liquid Phase Separation in Living Cells
We introduce the Composition of LLPS proteome Assembly by Proximity labeling assisted Mass spectrometry (CLAPM) to address such unmet need in this filed. We demonstrate CLAPM for instantaneously labeling and monitoring in situ proteome shifts within intracellular droplets that undergo spatiotemporal...
ORGANISM(S): Homo sapiens (Human) 
2025-03-26 | PXD051405 | Pride
Liquid-liquid phase separations  proximity labeling  proteomics  mass spectrometry  living cells  
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