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In lupus autoimmunity, pathogenic IgG autoantibodies that fix complement and bind FcGammaR on inflammatory cells, are produced with help from T helper (Th1 and Th17) cells specific for peptides from nucleosomes of apoptotic cells; and these Th cells also infiltrate vital organs (1-9). Macrophages (...
ORGANISM(S): Mus musculus 
The de novo DNA methyltransferase DNMT3B functions in establishing DNA methylation patterns during development. We performed RNAi knockdown of DNMT3B in human embryonic stem cells (ESCs) in order to investigate the mechanistic contribution of DNMT3B on DNA methylation and early neuronal differentiat...
ORGANISM(S): Homo sapiens 
H441 cell proteome was sequenced via SILAC and LC-MS/MS method to identify hypoxia-responsive proteins
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-05-15 | MSV000081087 | MassIVE
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