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MetabolomicsAnalysis of the human adult urinary metabolome variations with age, body mass index and gender by implementing a comprehensive workflow for univariate and OPLS statistical analyses. ('Sacurine' data set)

Urine metabolomics is widely used for biomarker research in the fields of medicine and toxicology. As a consequence, characterization of the variations of the urine metabolome under basal conditions becomes critical in order to avoid confounding effects in cohort studies. Such physiological infor...

2017-01-20 | MTBLS404 | MetaboLights
UnknownPresence of qnr gene in Escherichia coli and Klebsiella pneumoniae resistant to ciprofloxacin isolated from pediatric patients in China.
Not available
S-EPMC2409344 | biostudies-literature
UnknownTherapeutic strategies and treatment sequencing in patients with chronic lymphocytic leukemia: An international study of ERIC, the European Research Initiative on CLL.
Not available
S-EPMC11405932 | biostudies-literature
UnknownOther malignancies in the history of CLL: an international multicenter study conducted by ERIC, the European Research Initiative on CLL, in HARMONY.
Not available
S-EPMC10685149 | biostudies-literature
MetabolomicsMultiomic profiling of iron-deficient infant monkeys reveals alterations in neurologically important biochemicals in serum and cerebrospinal fluid before the onset of anemia

The effects of iron deficiency (ID) during infancy extend beyond the hematologic compartment and include short- and long-term adverse effects on many tissues including the brain. However, sensitive biomarkers of iron-dependent brain health are lacking in humans. To determine whether serum and cer...

2022-07-12 | MTBLS3388 | MetaboLights
TranscriptomicsExpression data for HT29 cells treated with 5-aza-deoxy-cytidine [RNA-Seq]
The RNA samples from HT-29 (ATCC) colon cancer cell line were reverse transcribed to build cDNA libraries and categorized into 3 groups with different concentrations of 5-aza-deoxy-cytidine (5-Aza); in each group three replicative 150 mm cultures were treated with: 1) dimethyl sulfoxide (vehicle alo...
ORGANISM(S): Homo sapiens 
2013-09-17 | E-GEOD-41586 | biostudies-arrayexpress
UnknownTP53 Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children.
Not available
S-EPMC5815403 | biostudies-literature
ModelsGonzalez2021 - QSAR Prediction Model for CYP2D6 Inhibitor and Substrate
Analysis of metabolic stability, determining the inhibition of CYP2D6 activity and whether the compounds are a substrate for the CYP2D6 enzyme. The data used to build these models has been publicly available at PubChem (AID1645840) by ADME@NCATS. Model Type: Predictive machine learning model. Model...
2024-05-10 | MODEL2404160003 | BioModels
Machine Learning Model Ersilia 
ModelsGonzalez2021 - QSAR Prediction Model for CYP450 enzymes Inhibitor and Substrate
Analysis of metabolic stability, determining the inhibition of CYP450 activity and whether the compounds are a substrate for the CYP450 enzymes. The data used to build these models is publicly available at PubChem (AID1645840, AID1645841, AID1645842). The tested cyps include CYP2C9, CYP2D6 and CYP3A...
2024-05-10 | MODEL2404160004 | BioModels
Machine Learning Model Ersilia 
ModelsGonzalez2021 - QSAR Prediction Model for CYP3A4 Inhibitor and Substrate
Analysis of metabolic stability, determining the inhibition of CYP3A4 activity and whether the compounds are a substrate for the CYP3A4 enzyme. The data used to build these models has been publicly available at PubChem (AID1645841) by ADME@NCATS. Model Type: Predictive machine learning model. Model...
2024-05-10 | MODEL2404160001 | BioModels
Machine Learning Model Ersilia 
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