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ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM_CBFB_CUL2_CUL5_interactors
SRM assays were generated for selected interactors of CUL5, CBFB and ELOB. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated fro...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084965 | MassIVE
ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM-CBFB
SRM assays were generated for selected interactors of CBFB. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated from the shotgun M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084964 | MassIVE
ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM-ELOB
SRM assays were generated for selected interactors of ELOB. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated from the shotgun M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084962 | MassIVE
ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM-CUL5
SRM assays were generated for selected interactors of CUL5. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated from the shotgun M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084963 | MassIVE
ProteomicsARIH2 is a novel Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection
Discovery of novel host-virus interactions leads to a better understanding of mechanisms underlying infection and points to potential therapeutic targets at the interface between virus and host proteins. Recently, global, virus-host interaction networks have been mapped using affinity purification-m...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-29 | MSV000084855 | MassIVE
UnknownA proximity proteomics pipeline with improved reproducibility and throughput
Not available
S-SCDT-10_1038-S44320-024-00049-2 | biostudies-other
ProteomicsPotential binding partners of NUDT13 in DLD-1
To explore the role of NUDT13 in the initiation and progression of CRC, we performed NUDT13 immunoprecipitation in DLD-1 following LC-MS/MS analysis.
ORGANISM(S): Homo Sapiens 
2023-04-08 | PXD041430 |
ProteomicsProfiling the diversity of agonist-selective effects on the proximal proteome environment of G protein-coupled receptors
G-protein coupled receptors (GPCRs) regulate various aspects of cellular behavior and represent actionable targets for drug discovery. Activation of specific signaling pathways downstream of G-protein coupled receptors (GPCRs) or targeting the receptors at selected cellular locations has the potenti...
ORGANISM(S): Homo Sapiens 
2024-03-31 | PXD031393 | panorama
ProteomicsSmoothened Transduces Hedgehog Signals via Activity-Dependent Sequestration of PKA Catalytic Subunits
The Hedgehog (Hh) pathway is essential for organ development, homeostasis, and regeneration. Dysfunction of this cascade drives several cancers. To control expression of pathway target genes, the G protein-coupled receptor (GPCR) Smoothened (SMO) activates glioma-associated (GLI) transcription facto...
ORGANISM(S): Homo Sapiens 
PXD023893 | panorama
ProteomicsThe Global Phosphorylation Landscape of SARS-CoV-2 Infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19) pandemic, has infected over 3 million people worldwide and caused over 200,000 deaths since it emerged in late 2019. There is an urgent need to develop therapies that can limi...
ORGANISM(S): Chlorocebus Aethiops (ncbitaxon:9534) 
2020-07-15 | MSV000085759 | MassIVE
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