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GenomicsRole of PRC2 complex components in prostate cancer cell lines
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-39461 | biostudies-arrayexpress
TranscriptomicsExpression data of EZH2-dependent genes in prostate cancer cell lines
EZH2 is frequently over-expressed in aggressive and metastatic solid tumors, including castration resistant prostate cancer (CRPC). We sought to determine EZH2-dependent gene expression programmes in prostate cancer progression, and found an intriguing functional switch of EZH2 from a repressor to a...
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-39452 | biostudies-arrayexpress
GenomicsGemone-wide maps of PRC2 complex components and chromatin states in prostate cancer cell lines
We report the high-throughput profiling of PRC2 core subunits chromatin states and histone modifications in two prostate cancer cell lines, androgen-dependent cells LNCaP and androgen-independent cells LNCaP-abl (abl). By obtaining over 1 billion bases of sequence from chromatin immunoprecipitated D...
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-39459 | biostudies-arrayexpress
ProteomicsThe disturbance of lipid metabolism by the TNF-α /PLEKHA5/FCRLA axis leads to the proliferation, invasion and metastasis of cutaneous malignant melanoma
Background: Cutaneous malignant melanoma (CMM) is one of the most highly fatal cancers; its pathogenesis requires study. We recognize that abnormalities in lipid metabolism may be associated with the risk of CMM development; nevertheless, the role of lipid metabolism in the proliferation, invasion, ...
ORGANISM(S): Homo Sapiens 
2024-08-12 | PXD054835 |
UnknownTBL1X and Flot2 form a positive feedback loop to promote metastasis in nasopharyngeal carcinoma.
Not available
S-EPMC8771836 | biostudies-literature
Metabolomicsuntargeted metabolomic profiling of colonic contents

Pre-IBD is a transitional state between irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), in which chronic high-fat diet intake and antibiotic exposure significantly increase intestinal inflammatory susceptibility. However, the underlying mechanisms and effective therapeutic st...

2026-04-29 | MTBLS14400 | MetaboLights
MetabolomicsLipidomics of colon tissues

Pre-IBD is a transitional state between irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), in which chronic high-fat diet intake and antibiotic exposure significantly increase intestinal inflammatory susceptibility. However, the underlying mechanisms and effective therapeutic st...

2026-04-29 | MTBLS14399 | MetaboLights
UnknownPCSK9 inhibition interrupts the cross-talk between keratinocytes and macrophages and prevents UVB-induced skin damage.
Not available
S-EPMC10331474 | biostudies-literature
UnknownCRISPR-Cas9-guided amplification-free genomic diagnosis for familial hypercholesterolemia using nanopore sequencing.
Not available
S-EPMC10954175 | biostudies-literature
UnknownFumarate Hydratase Enhances the Therapeutic Effect of PD-1 Antibody in Colorectal Cancer by Regulating PCSK9.
Not available
S-EPMC10887080 | biostudies-literature
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