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MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
UnknownThe Simultaneous Determination of Chlorpyrifos-Ethyl and -Methyl with a New Format of Fluorescence-Based Immunochromatographic Assay.
Not available
S-EPMC9688337 | biostudies-literature
UnknownTaxonomic notes on <i>Neocinnamomum</i> (Lauraceae): a new combination and a new species from southwestern China.
Not available
S-EPMC12831112 | biostudies-literature
UnknownEssential function of transmembrane transcription factor MYRF in promoting transcription of miRNA lin-4 during C. elegans development.
Not available
S-EPMC11223767 | biostudies-literature
ProteomicsPreferential phosphorylation on old histones during early mitosis in human cells
How histone posttranslational modifications (PTMs) are inherited through cell cycle remains poorly understood. Canonical histones are made in the S phase of cell cycle. Combining mass spectrometry-based technologies and stable isotope labeling by amino acids in cell culture (SILAC), we interrogate t...
ORGANISM(S): Homo sapiens (Human) 
2016-06-01 | PXD003709 | Pride
Mass spectrometry Mitosis Histone modifications Cell cycle Histone phosphorylation 
TranscriptomicsGene expression profiling of novel antigen presenting cells (APC) inducing pathogenic T helper cells of lupus
In lupus autoimmunity, pathogenic IgG autoantibodies that fix complement and bind FcGammaR on inflammatory cells, are produced with help from T helper (Th1 and Th17) cells specific for peptides from nucleosomes of apoptotic cells; and these Th cells also infiltrate vital organs (1-9). Macrophages (...
ORGANISM(S): Mus musculus 
2012-06-20 | E-GEOD-36284 | biostudies-arrayexpress
UnknownPhysiological Mechanisms and Core Genes in Response to Saline-Alkali Stress in Foxtail Millet (<i>Setaria italica</i> L.).
Not available
S-EPMC12190892 | biostudies-literature
UnknownHepatic actinomycosis: report of one case and analysis of 32 previously reported cases.
Not available
S-EPMC4239533 | biostudies-literature
TranscriptomicsTranscriptome profiling in reciprocal hybrids and tetraploids constructed from subspecies japonica and indica of Asian rice (Oryza sativa L.)
Hybrids and allopolyploids typically exhibit radically altered gene expression patterns relative to their parents, a phenomenon termed “transcriptomic shock.” To distinguish the effects of hybridization from polyploidization on coregulation of divergent alleles, we analyzed expression of parenta...
ORGANISM(S): Oryza sativa 
2014-02-18 | E-MTAB-4271 | biostudies-arrayexpress
UnknownLin- PU.1dim GATA-1- defines haematopoietic stem cells with long-term multilineage reconstitution activity.
Not available
S-EPMC10623959 | biostudies-literature
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