Sort   by:  
 Page size 
UnknownEffect of oral Xiao-xian decoction combined with acupoint application therapy on pediatric adenoid hypertrophy: A randomized trial.

Background

This study aimed to observe the clinical effects of Xiao-xian decoction combined with acupoint application therapy (AAT) for treating pediatric adenoid hypertrophy (AH).

Methods

We randomly divided 93 AH children into 3 groups: AAT alone; Xiao-xian decoction + AAT; control:...
S-EPMC9901993 | biostudies-literature
UnknownUnderstanding the polypharmacological anticancer effects of Xiao Chai Hu Tang via a computational pharmacological model.
Xiao Chai Hu Tang (XCHT), a traditional herbal formula, is widely administered as a cancer treatment. However, the underlying molecular mechanisms of its anticancer effects are not fully understood. In the present study, a computational pharmacological model that combined chemical space mapping, mol...
S-EPMC4043560 | biostudies-literature
UnknownSteroid hormone-deprived sex reversal in cyp11a1 mutant XX tilapia experiences an ovary-like stage at molecular level.
Fish sex is largely influenced by steroid hormones, especially sex hormones. Here, we established a steroid hormone-free genetic model by mutation of cyp11a1 in Nile tilapia, which was confirmed by EIA assay. Gonadal phenotype and transcriptome analyses showed that the XX mutants displayed sex rever...
S-EPMC11405705 | biostudies-literature
UnknownHepatic actinomycosis: report of one case and analysis of 32 previously reported cases.
Hepatic actinomycosis is rare, with few published cases. There are no characteristic clinical manifestations, and computed tomography (CT) shows mainly low-density images, making clinical diagnosis difficult, and leading to frequent misdiagnosis as primary liver cancer, metastatic liver cancer or li...
S-EPMC4239533 | biostudies-literature
UnknownAutofluorescence imaging endoscopy can distinguish non-erosive reflux disease from functional heartburn: A pilot study.

Aim

To investigate whether autofluorescence imaging (AFI) endoscopy can distinguish non-erosive reflux disease (NERD) from functional heartburn (FH).

Methods

In this prospective observational trial, 127 patients presenting with typical reflux symptoms for > 6 mo were screened. All the...
S-EPMC4814748 | biostudies-literature
UnknownTele-Cognitive Behavioral Therapy for the Treatment of Diabetes-Related Distress in Individuals With Diabetes Mellitus: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Background

Diabetes-related distress (DD) is highly prevalent in individuals with diabetes mellitus (DM) and impairs quality of life. Tele-cognitive behavioral therapy (Tele-CBT) shows potential for reducing DM-related psychological distress; prior research focused primarily on in-person cog...
S-EPMC12736637 | biostudies-literature
UnknownEfficacy and safety of Xiangsha Liujunzi granules for functional dyspepsia: A multi-center randomized double-blind placebo-controlled clinical study.

Aim

To assess the efficacy and safety of a Chinese herbal medicine (CHM), Xiangsha Liujunzi granules, in the treatment of patients with functional dyspepsia (FD).

Methods

We performed a randomized, double-blind, placebo-controlled trial with patients from three centers. Two hundred an...
S-EPMC5558122 | biostudies-literature
MetabolomicsComparison of the Metabolic Profiles in the Plasma and Urine Samples Between Autistic and Typically Developing Boys: A Preliminary Study
Background: Autism spectrum disorder (ASD) is defined as a pervasive developmental disorder which is caused by genetic and environmental risk factors. Besides the core behavioral symptoms, accumulated results indicate children with ASD also share some metabolic abnormalities. Objectives:
2022-03-02 | MTBLS2421 | MetaboLights
UnknownThe Oncologist, 2025, Vol, XX, Issue XX Predictive role of ARID1A and B2M mutations and the antigen presentation pathway in the efficacy of definitive chemoradiotherapy for cervical cancer.

Background and purpose

Definitive chemoradiotherapy (dCRT) is the standard treatment for locally advanced cervical cancer (LACC), yet patients experience considerable variability in disease-free survival (DFS). This study aimed to identify molecular biomarkers associated with response to dCR...
S-EPMC12204396 | biostudies-literature
MetabolomicsCD73 inhibitor AB680 suppresses glioblastoma in mice by inhibiting purine metabolism and promoting P2RY12<sup>+</sup> microglia transformation.
CD73 (ecto-5'-nucleotidase) is a metabolic immune checkpoint that dephosphorylates AMP to produce adenosine. Adenosine plays a pivotal role in immunosuppressive tumor microenvironment (TME) through adenosine receptors expressed on various immune cells. AB680, a specific CD73 inhibitor, is currently ...
2025-08-04 | MTBLS11084 | MetaboLights
Sort   by:  
 Page size