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ProteomicscTAGE5/MEA6 regulates LBR transport to maintain nuclear envelope integrity and safeguard against aging
IP-MS of fused MEA6-GFP and the control sample were performed. For MS analyses, peptides were resuspended in 0.1% FA and analyzed by LTQ Orbitrap Elite mass spectrometer (ThermoFisher Scientific) coupled online to an Easy-nLC 1000 (Thermo Fisher Scientific) in the data-dependent mode.
ORGANISM(S): Homo Sapiens 
2025-04-24 | PXD063263 |
ProteomicsFunctional identification of protocadherin alpha 9 (PCDHA9) as a candidate causative gene for amyotrophic lateral sclerosis
Mice were sacrificed after anesthesia by isoflurane following neck cutting. The spinal cord L3-L5 was taken and frozen in liquid nitrogen immediately and the ventral horn of the bilateral spinal cord (about 400um thick in gray matter area) was collected at low temperature. The samples were digested ...
ORGANISM(S): Mus Musculus 
2023-06-12 | PXD042929 |
ProteomicscTAGE5 is essential for adipogenesis and adipose tissue development
White adipocytes serve as primary energy reservoirs and their malfunction is linked to different metabolic disorders, yet the mechanisms underlying cellular specialization, a critical step during adipogenesis remain unknown. Here, we reveal the indispensable role of cutaneous T cell lymphoma-associa...
ORGANISM(S): Mus Musculus 
2025-01-07 | PXD059525 |
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