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MetabolomicsPu-erh tea and theabrownin ameliorate metabolic syndrome in mice via potential microbiota-gut-liver-brain interactions
Metabolic syndrome (MS) is a common metabolic disorder characterized by obesity, insulin resistance, cardiovascular disease and gut microbiota dysbiosis. Pu-erh tea and its ingredient theabrownin have known functions on the reduction of body weight gain and fat accumulation. However, few studies sys...
2024-09-25 | MTBLS2594 | MetaboLights
ProteomicsQuantitative proteomic analysis of polarized macrophages
In this study, by using two classical macrophage cell models, RAW264.7 cell line from mouse and THP-1 cell line from human, combined with the applications of two classical stimulation methods for inducing classical activated (M1) and alternatively activated macrophages (M2) from the monocytes of bot...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2021-06-18 | PXD019800 | Pride
Macrophage Polarization Lc-ms/ms 
ProteomicsA synthetic antibiotic class with a deeply-optimized design for overcoming bacterial resistance
The lack of new drugs that are effective against antibiotic-resistant bacteria has caused increasing concern in global public health. Based on this study, we report development of a modified antimicrobial drug through structure-based drug design (SBDD) and modular synthesis. The optimal modified com...
ORGANISM(S): Staphylococcus Aureus 
2024-06-24 | PXD053342 |
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