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GenomicsThe conserved role of the RSC chromatin remodeler in the establishment of nucleosome depleted regions
The occupancy of nucleosomes governs access to the eukaryotic genomes and results from a combination of biophysical features and the effect of ATP-dependent remodeling complexes. Most promoter regions show a conserved pattern characterized by a nucleosome-depleted region (NDR) flanked by nucleosomal...
ORGANISM(S): Schizosaccharomyces pombe 
2016-08-24 | E-GEOD-84912 | biostudies-arrayexpress
GenomicsHistone H2B ubiquitylation represses gametogenesis by opposing RSC-Dependent chromatin remodeling at the ste11 master regulator locus
Chromatin modifications play a pivotal role in cell fate decision. In fission yeast, the ste11 gene encodes the master regulator initiating the switch from vegetative growth to gametogenesis when cells starve. The methylation of H3K4 by Set1-COMPASS and consequent promoter nucleosome deacetylation w...
ORGANISM(S): Schizosaccharomyces pombe 
2016-07-22 | E-GEOD-80524 | biostudies-arrayexpress
GenomicsPromoter nucleosome dynamics regulated by signaling through the CTD code
Sequencing of mononucleosomal DNA from asynchronous cells of Schizosaccharomyces pombe WT and S2A mutant Mononucleosomal DNA from asynchronous S. pombe WT (1 sample) and S2A mutant cells (2 samples) were sequenced (Illumina HiSeq 2000) using the single-end read protocol
ORGANISM(S): Schizosaccharomyces pombe 
2015-06-22 | E-GEOD-59768 | biostudies-arrayexpress
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