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TranscriptomicsGene expression analysis of Influenza vaccine response in Young and Old - Year 1
We profiled gene expression from a stratified cohort of subjects to define influenza vaccine response in Young and Old Differential gene expression by human PBMCs from Healthy Adults receiving Influenza Vaccination (Fluvirin, Novartis). Healthy adults (older >65, younger 21-30 years) were recruited ...
ORGANISM(S): Homo sapiens 
2015-01-26 | E-GEOD-59635 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of Influenza vaccine response in Young and Old - Year 2
We profiled gene expression from a stratified cohort of subjects to define influenza vaccine response in Young and Old Differential gene expression by human PBMCs from Healthy Adults receiving Influenza Vaccination (Fluvirin, Novartis). Healthy adults (older >65, younger 21-30 years) were recruited ...
ORGANISM(S): Homo sapiens 
2015-01-26 | E-GEOD-59654 | biostudies-arrayexpress
TranscriptomicsDynamic expression profiling of type I and type III interferon-stimulated hepatocytes.
This dataset details the time-dependent response of human Huh7 hepatoma cells to type I and type III IFN. Despite activating similar signaling cascades, the type I and type III interferons (IFNs) differ in their ability to antagonize viral replication. However, it is not clear whether these cytokine...
ORGANISM(S): Homo sapiens 
2013-08-22 | E-GEOD-48400 | biostudies-arrayexpress
TranscriptomicsThe blood transcriptional signature of chronic HCV [Illumina data]
This study characterizes the effects of chronic Hepatitis C virus (HCV) infection on gene expression by analyzing blood samples from 10 treatment-naive HCV patients and 6 healthy volunteers. Differential expression analysis of microarray data from peripheral blood mononuclear cells (PBMCs) identifie...
ORGANISM(S): Homo sapiens 
2012-10-22 | E-GEOD-40223 | biostudies-arrayexpress
ProteomicsSimple, single-shot phosphoproteomic analysis of heat-stable tau
We developed a simple, antibody-free approach for single shot analysis of tau phosphorylation across the entire protein by liquid-chromatography tandem mass spectrometry (LC-MS/MS) to study age-related changes in tau phosphorylation. This methodology is species independent; thus, while initially dev...
ORGANISM(S): Rattus norvegicus (Rat) Macaca mulatta (Rhesus macaque) 
2021-11-25 | PXD027971 | Pride
Phosphoproteomics Brain Tau Heat-stable 
UnknownThe Lyme disease agent co-opts adiponectin receptor-mediated signaling in its arthropod vector.
Not available
S-EPMC8639152 | biostudies-literature
UnknownA fluorescence-based assay for measuring polyamine biosynthesis aminopropyl transferase-mediated catalysis.
Not available
S-EPMC11541840 | biostudies-literature
UnknownSpecific and Sensitive Diagnosis of Babesia microti Active Infection Using Monoclonal Antibodies to the Immunodominant Antigen BmGPI12.
Not available
S-EPMC9491189 | biostudies-literature
UnknownRepeat tick exposure elicits distinct immune responses in guinea pigs and mice.
Not available
S-EPMC7530331 | biostudies-literature
UnknownAn Ixodes scapularis Protein Disulfide Isomerase Contributes to Borrelia burgdorferi Colonization of the Vector.
Not available
S-EPMC7671890 | biostudies-literature
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