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TranscriptomicsTet proteins in DNA demethylation and cell fate restriction
DNA methylation at 5-position of cytosine (5mC) is one of the best studied epigenetic modifications that plays important roles in diverse biological processes. Iterative oxidation of 5mC by the Ten-eleven translocation (Tet) family of proteins generates 5-hydroxymethylcytosine (5hmC), 5-formylcytosi...
ORGANISM(S): Mus musculus 
2014-09-22 | E-GEOD-56986 | biostudies-arrayexpress
GenomicsGenome-wide analysis reveals TET- and TDG-mediated 5-methylcytosine oxidation dynamics [MeDIP-Seq]
Ten-eleven translocation (Tet) family of DNA dioxygenases converts 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5- carboxylcytosine (5caC) through iterative oxidation reactions. While 5mC and 5hmC are relatively abundant, 5fC and 5caC are at very low levels...
ORGANISM(S): Mus musculus 
2013-04-18 | E-GEOD-46111 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis reveals TET- and TDG-mediated 5-methylcytosine oxidation dynamics [Expression]
Ten-eleven translocation (Tet) family of DNA dioxygenases converts 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5- carboxylcytosine (5caC) through iterative oxidation reactions. While 5mC and 5hmC are relatively abundant, 5fC and 5caC are at very low levels...
ORGANISM(S): Mus musculus 
2013-04-18 | E-GEOD-46112 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis reveals TET- and TDG-mediated 5-methylcytosine oxidation dynamics
Ten-eleven translocation (Tet) family of DNA dioxygenases converts 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5- carboxylcytosine (5caC) through iterative oxidation reactions. While 5mC and 5hmC are relatively abundant, 5fC and 5caC are at very low levels...
ORGANISM(S): Mus musculus 
2013-04-18 | E-GEOD-42250 | biostudies-arrayexpress
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