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UnknownAssociation of ITPA polymorphism with outcomes of peginterferon-α plus ribavirin combination therapy.
Not available
S-EPMC3729868 | biostudies-literature
TranscriptomicsThe Kinase SGK1 in the Endoderm and Mesoderm Promotes Ectodermal Survival by Downregulating Components of the Death-Inducing Signaling Complex
A balance between cell survival and apoptosis is essential for animal development. Although proper development involves multiple interactions between germ layers, little is known about the intercellular and intertissue signaling pathways that promote cell survival in neighboring or distant germ laye...
ORGANISM(S): Xenopus laevis 
2011-02-21 | E-GEOD-26381 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Trib1-deficient animals vs controls
The purpose of this experiment was to compare the gene expression pattern between wild-type and Trib1-deficient macrophages in response to LPS. Experiment Overall Design: Two samples to define LPS-inducible gene and 4 samples (2 for wild-type and the rests for Trib1-deficient mice) for comparison.
ORGANISM(S): Mus musculus 
2008-11-06 | E-GEOD-8788 | biostudies-arrayexpress
TranscriptomicsExpression data from various tomato plant tissues
Gene-to-gene coexpression analysis is a powerful approach to infer function of uncharacterized genes. To perform non-targeted coexpression analysis of tomato genes, we collected a developmental gene expression dataset using various tissues of tomato plant. Expression data are collected from 24 diffe...
ORGANISM(S): Solanum lycopersicum 
2010-02-21 | E-GEOD-19326 | biostudies-arrayexpress
ProteomicsLFQ of mNeonGreen-Trap IP-MS from cells expressing HKDC1-mNeonGreen
Cells stably expressing full-length HKDC1-mNeonGreen or △N20 HKDC1-mNeonGreen proteins were grown in a 10-cm dish and were treated with or without antimycin/oligomycin for 3h, and then cross-linked with 0.1% formaldehyde for 10min at room temperature. After cross-linking was quenched with 100mM glyc...
ORGANISM(S): Homo Sapiens (human) 
2024-01-21 | PXD040970 | JPOST Repository
ProteomicsPIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation
Proteomic analysis revealed potential phospho-acceptor sites within Vpx by PIM3. HEK293 cells were transfected with plasmid vector encoding Vpx together with either empty vector or PIM3. Immunoprecipitated Vpx was subjected to liquid chromatography tandem-mass spectrometry.
ORGANISM(S): Homo Sapiens (human) 
2019-03-20 | PXD013154 | JPOST Repository
ProteomicsChanges in the astronaut serum proteome during prolonged spaceflight
The molecular mechanisms associated with spaceflight-induced biological adaptations that may affect many healthy tissue functions remain poorly understood. In this study, we analyzed temporal changes in the serum proteome of six astronauts during prolonged spaceflight missions using quantitative com...
ORGANISM(S): Homo Sapiens (human) 
2024-01-22 | PXD044609 | JPOST Repository
ProteomicsPost-transcriptionally regulated genes are essential for pluripotent stem cell survival
Here, by combining transcriptome and proteome profiling, we identified 228 post-transcriptionally regulated genes with strict regulation at the protein level in PSCs. Among them, 84 genes were found necessary for the survival of several cell types including PSCs, and 20 genes were identified as spec...
ORGANISM(S): Homo Sapiens (human) 
2022-05-10 | PXD028489 | JPOST Repository
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