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TranscriptomicsZscan10 is dispensable for maintenance of pluripotency in mouse embryonic stem cells
Zinc finger and SCAN domain-containing 10 (Zscan10, also known as Zfp206) encodes a transcription factor that has been reported to be involved in the maintenance of pluripotency in mouse embryonic stem (ES) cells. Here we generated inducible knockout ES cells for Zscan10 using the Cre-loxP system an...
ORGANISM(S): Mus musculus 
2015-12-20 | E-GEOD-76143 | biostudies-arrayexpress
TranscriptomicsGata6 induced XEN-like cells w/o Sox7
To understand the role of Sox7 in primitive endoderm differentiation, we compare the gene expression pattern of Sox7 (+/-) and Sox7 (-/-) ES cells with or without dexamethasome (Dex) treatment. Because these ES cells harbour Gata6-GR transgene, Dex treatment forces ES cells differentate into XEN-lik...
ORGANISM(S): Mus musculus 
2015-09-14 | E-GEOD-66971 | biostudies-arrayexpress
TranscriptomicsThe C-terminal region of Xpc is dispensable for the transcriptional activity of Oct3/4 in mouse embryonic stem cells
The transcription factor Oct3/4 is essential to maintain pluripotency in mouse embryonic stem (ES) cells. It was reported that the Xpc DNA repair complex is involved in this process. Here we examined the role of Xpc on the transcriptional activation of the target genes by Oct3/4 using the inducible ...
ORGANISM(S): Mus musculus 
2015-06-09 | E-GEOD-69640 | biostudies-arrayexpress
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