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ProteomicsDNA damage response signaling to mitochondria drives senescence
Cellular senescence is a stress-induced permanent cell cycle arrest typically accompanied by expression of the cyclin-dependent kinase inhibitor p16. Recent studies have suggested that p16-expressing senescent cells accumulate in the body with age and play a causative role in aging. Various stresses...
ORGANISM(S): Homo sapiens (Human) 
2025-01-14 | PXD036980 | Pride
Human Lc-ms/ms 
ProteomicsPhosphorylation of two Thr residues in the C-terminal auto-inhibitory domain of plasma membrane H+-ATPase is crucial for light-induced stomatal opening
Plasma membrane H+-ATPase provides the driving force for light-induced stomatal opening. However, the mechanisms underlying the regulation of its activity remain unclear. Here, we showed that the phosphorylation of two Thr residues in the C-terminal autoinhibitory domain is crucial for H+-ATPase act...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2023-12-25 | PXD039740 | JPOST Repository
ProteomicsPhosphorylation of two Thr residues in the C-terminal auto-inhibitory domain of plasma membrane H+-ATPase is crucial for light-induced stomatal opening-2
Plasma membrane H+-ATPase provides the driving force for light-induced stomatal opening. However, the mechanisms underlying the regulation of its activity remain unclear. Here, we showed that the phosphorylation of two Thr residues in the C-terminal autoinhibitory domain is crucial for H+-ATPase...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2023-12-25 | PXD044476 | JPOST Repository
ProteomicsPhosphorylation of WDR48 by phototropins drives starch degradation to promote stomatal opening
Plant stomata open in response to blue light under a background of red light. Red light induces starch accumulation through guard cell photosynthesis, whereas blue light causes rapid starch degradation via the activation of plasma membrane H+-ATPase through phosphorylation of BLUS1 by phototropins, ...
ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress) 
2026-02-18 | PXD073138 | JPOST Repository
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