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ProteomicsIntegrated Proteomic and Metabolomic Analysis of Muscle Atrophy Induced by Hindlimb Unloading
Skeletal muscle atrophy, which is induced by factors such as disuse, spaceflight, certain medications, neurological disorders, and malnutrition, is a global health issue lacking effective treatment. Hindlimb unloading is a commonly used model for muscle atrophy. However, the underlying mechanism of ...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-05-07 | PXD057671 | Pride
Muscle atrophy  hindlimb unloading  proteomics  metabolomics  integrated analysis 
Proteomics[HPP-2.0] Matrix Thermal Shift Assay for Fast Construction of Multidimensional Ligand–Target Space
Existing thermal shift-based mass spectrometry approaches are able to identify target proteins without chemical modification of the ligand, but they are suffering from complicated workflows with limited throughput. Herein, we present a new thermal shift-based method, termed matrix thermal shift assa...
ORGANISM(S): Homo Sapiens 
2023-09-29 | PXD045941 |
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