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MetabolomicsAirway Dysbiosis Accelerates Lung Function Decline in Chronic Obstructive Pulmonary Disease (Human UPLC-MS/MS assays)

Progressive decline in lung function is a hallmark of chronic obstructive pulmonary disease (COPD). Although airway dysbiosis occurs in COPD, whether it contributes to disease progression remains unknown. Here, through a longitudinal analysis on 181 COPD individuals from two large cohorts involvi...

2023-06-12 | MTBLS5423 | MetaboLights
ProteomicsComparative analysis of N-glycoproteome differences between the mutant mld1 and wild-type Aichiasahi
Protein N- glycosylation is one of the major post-translational modifications in eukaryotic cells. In plants, complex N-glycans are important for developmental programs and immune responses. In animals, Malectin selectively binds carbohydrates for diglucose and high-mannose N-glycans and forms a sta...
ORGANISM(S): Oryza Sativa 
2022-05-17 | PXD033933 |
TranscriptomicsIntegration of developmental and nutritional cues determines timing of female flower opening in cucumber
The timing of flower opening is essential for pollination and thus seed production. Despite flower opening has been a long lasting topic for plant biologists, the underling molecular mechansim remains elusive. Here we used a unique cucumber line ‘6457’ that spontaneously produces super ovary wit...
ORGANISM(S): Cucumis sativus 
2016-07-25 | E-GEOD-76358 | biostudies-arrayexpress
TranscriptomicsAnalysis the Ability of Producing Secondary Metabolites of Streptomyces bingchenggensis By The Genome Sequence and GeneChip DNA microarrays
Streptomyces bingchenggensis is a soil bacterium that produces a family of macrolide antibiotics, milbemycins, which is commercially important in crop protection, human and veterinary medicine. After the complete genome sequence, and annotation, for further development of our gene expression approac...
ORGANISM(S): Streptomyces bingchenggensis 
2011-09-19 | E-GEOD-32205 | biostudies-arrayexpress
ProteomicsQuantitative proteomic analysis of iron oxide nanoparticles toxicity in rats
Iron oxide nanoparticles (IONPs) are the first generation of nanomaterials approved by the Food and Drug Administration for use as imaging agents and for the treatment of iron deficiency in chronic kidney disease. However, several IONPs-based imaging agents have been withdrawn because of toxic effec...
ORGANISM(S): Rattus Norvegicus 
2022-08-11 | PXD035970 |
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