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Microproteins are generated from small open reading frames (sORFs) and turn out to play various vital biological functions. As an essential biological event of eukaryotic cells, the cell cycle is involved in cell replication and division. For such a highly regulated event, microproteins associated w...
ORGANISM(S): Homo Sapiens 
2021-12-09 | PXD030286 |
Here we used mass spectrometry-based proteomics technology to explore SEPs with potential cellular stress function in Saccharomyces cerevisiae. Microproteins with unique peptides were identified under six culture conditions: normal, oxidation, starvation, UV radiation, heat shock, and heat shock wit...
ORGANISM(S): Saccharomyces Cerevisiae 
2022-06-07 | PXD028623 |
We used phosphoproteomic profiling of slow-twitch (soleus, SOL) and fast-twitch (biceps femoris, BF) muscle to identify differences between these muscle types.
ORGANISM(S): Sus Scrofa Domesticus 
2022-08-16 | PXD036066 |
We provide a proteomic profile for fast/glycolytic biceps femoris (BF) and slow/oxidative soleus (SOL) muscles using tandem Mass Tags (TMT)-based proteomic analysis.
ORGANISM(S): Sus Scrofa Domesticus 
2022-11-27 | PXD038446 |
Mutations or aberrant upregulation of the histone methyltransferase EZH2 occur frequently in human cancers yet EZH2-targeted therapies have only shown very limited clinical benefits in hematological malignancies. We report here that upon EZH2 inhibition, MLL1 interacts with p300/CBP complex that dir...
ORGANISM(S): Homo Sapiens 
2018-09-10 | PXD010842 |
Epidermal growth factor receptor (EGFR) mutations are leading oncogenic drivers in non-small cell lung cancer (NSCLC). Many third-generation EGFR tyrosine kinase inhibitors (TKIs) have been developed to target EGFR T790M and activating mutations. Osimertinib (AZD9291) was the first approved drug and...
ORGANISM(S): Homo Sapiens 
2023-07-14 | PXD043776 |
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