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UnknownLeucine alleviates dexamethasone-induced suppression of muscle protein synthesis via synergy involvement of mTOR and AMPK pathways.
Not available
S-EPMC5293580 | biostudies-literature
GenomicsCellular generation of 5-Hydroxymethylcytosine by redox-active chemicals via an unprecedent non-enzymatic mechanism
We proposed that besides TET family dioxygenase oxidizing 5mC to 5hmC, there is a non-enzyme pathway which is due to hydroxyl radica l(OH) or OH-like species also involvement in demethylation of 5mC forming 5hmC. This pathway includes classical fenton reagents such as H2O2 and Fe2+, and more importa...
ORGANISM(S): Homo sapiens 
2013-12-05 | E-GEOD-44457 | biostudies-arrayexpress
UnknownHaematological and Biochemical Parameters of Captive Siberian Tigers (Panthera tigris altaica) from the Heilongjiang Province, China.
Not available
S-EPMC8136952 | biostudies-literature
GenomicsAscorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals.
DNA demethylation occurs in multiple cellular processes but its regulation is poorly understood. Here we report that a vital nutrient factor ascorbic acid (AA), or vitamin C (Vc), induces DNA demethylation in mammalian cells. The levels of active 5mC oxidation products, 5-formylcytosine and 5-carbox...
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-43262 | biostudies-arrayexpress
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