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Embryonic stem (ES) cells continuously decide whether to maintain pluripotency or differentiate. While exogenous LIF and BMP4 perpetuate a pluripotent state, less is known about factors initiating differentiation. We show that heparan sulfate (HS) proteoglycans are critical co-receptors for signals ...
ORGANISM(S): Mus musculus 
This model is according to the paper Dynamic Simulation on the Arachidonic Acid Metabolic Network . Figure 2A has been reproduced by SBML ode solver on line. In the original model, all the reactions are presented as ODE directly. So curator rewrite each reaction according to the seman...
2024-09-02 | BIOMD0000000106 | BioModels
This a model from the article: Population-based analysis of methadone distribution and metabolism using an age-dependent physiologically based pharmacokinetic model. Yang F, Tong X, McCarver DG, Hines RN, Beard DA. J Pharmacokinet Pharmacodyn 2006 Aug;...
2005-01-01 | MODEL1006230040 | BioModels
This is the arachidonic acid metabolic network model for human polymorphonuclear leukocyte (PMN) described in the article: Finding multiple target optimal intervention in disease-related molecular network. Yang K, Bai H, Ouyang Q, Lai L, Tang C. Mol Syst Biol. ...
2005-01-01 | MODEL8236441887 | BioModels
This is the arachidonic acid metabolic network model for human endothelial cells (EC) described in the article: Finding multiple target optimal intervention in disease-related molecular network. Yang K, Bai H, Ouyang Q, Lai L, Tang C. Mol Syst Biol. 20...
2005-01-01 | MODEL8236480549 | BioModels
This is the arachidonic acid metabolic network model for human platelet cells (PLT) described in the article: Finding multiple target optimal intervention in disease-related molecular network. Yang K, Bai H, Ouyang Q, Lai L, Tang C. Mol Syst Biol. 200...
2005-01-01 | MODEL8236520494 | BioModels
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