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MetabolomicsSnail reprograms glucose metabolism by repressing PFKP allowing cancer cell survival under metabolic stress
Dynamic regulation of glucose flux between aerobic glycolysis and the pentose phosphate pathway (PPP) during epithelial-mesenchymal transition (EMT) is not well-understood. Here we show that Snail (SNAI1), a key transcriptional repressor of EMT, regulates glucose flux toward PPP, allowing cancer cel...
2017-11-07 | MTBLS387 | MetaboLights
ProteomicsHuman skin fibroblast proteome in healthy aging
The changes in the proteome of different human tissues with advancing age are poorly characterized. Here, we studied the proteins present in skin fibroblasts collected from 82 healthy individuals across a wide age spectrum (22 to 89 years old) who participated in the GESTALT (Genetic and Epigenetic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-17 | MSV000088401 | MassIVE
UnknownlncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.
Not available
S-EPMC6143179 | biostudies-literature
UnknownSystematic Analysis of Splice-Site-Creating Mutations in Cancer.
Not available
S-EPMC6055527 | biostudies-literature
UnknownGenomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas.
Not available
S-EPMC6002769 | biostudies-literature
UnknownThe Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.
Not available
S-EPMC6075733 | biostudies-literature
UnknownThe Immune Landscape of Cancer.
Not available
S-EPMC5982584 | biostudies-literature
UnknownPan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas.
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S-EPMC5892207 | biostudies-literature
UnknownAn Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics.
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S-EPMC6066282 | biostudies-literature
UnknownMolecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers.
Not available
S-EPMC5916795 | biostudies-literature
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