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The PAF complex (Paf1C) has been shown to regulate chromatin modifications, gene transcription, and PolII elongation. Here, we provide the first genome-wide analysis of chromatin occupancy by the entire PAF complex in mammalian cells. We show that Paf1C is recruited not only to promoters and gene bo...
ORGANISM(S): Mus musculus 

Abstract

Background Doxorubicin (DOX), an anthracycline chemotherapeutic agent, is widely used for treating various malignancies. However, its clinical application is limited by dose-dependent cardiotoxicity (DOX-induced cardiotoxicity, DIC). Recent studies have shown that the gut microbiot...

2025-09-16 | MTBLS12997 | MetaboLights
Zou2012 - Genome-scale metabolic network of Ketogulonicigenium vulgare (iWZ663) This model is described in the article: Genome-scale metabolic model of Helicobacter pylori 26695. Schilling CH, Covert MW, Famili I, Church GM, Edwards JS, Palsson BO. J. Bacteriol. 2002 Aug; 184(...
2015-07-30 | MODEL1507180039 | BioModels
Transcriptional profiling of K. vulgare cells, co-cultured with Bacillus megaterium, comparing control untreated cells with cells treated with pH 4.0 for 2 h. Differentially expressed genes in acid-stressed cells were analyzed. The aim was to investigate the mechanisms of K. vulgare in response to a...
ORGANISM(S): Ketogulonicigenium vulgare 
The Journal of Experimental Medicine, Volume 194, Number 11, December 3, 2001 1639-1648 Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia Andreas Rosenwald1, Ash A. Alizadeh2, George Widhopf5, Richard Simon6, R. Eric Davis1, Xin Yu1, ...
ORGANISM(S): Homo sapiens 
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