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GenomicsHistone-fold domain protein NF-Y promotes chromatin accessibility for cell type-specific master transcription factors [ChIP-seq]
Cell type-specific master transcription factors (MTFs) play vital roles in defining cell identity and function. However, the roles ubiquitous factors play in the specification of cell identity remain underappreciated. Here we show that all three subunits of the ubiquitous heterotrimeric CCAAT-bindin...
ORGANISM(S): Mus musculus 
2014-08-14 | E-GEOD-56839 | biostudies-arrayexpress
MetabolomicshRUV: Hierarchical approach to removal of unwanted variation for large-scale metabolomics data
Liquid chromatography-mass spectrometry-based metabolomics studies are increasingly applied to large population cohorts, which run for several weeks or even years in data acquisition. This inevitably introduces unwanted intra- and inter-batch variations over time that can overshadow true biological ...
2021-07-05 | MTBLS2483 | MetaboLights
TranscriptomicsHistone-fold domain protein NF-Y promotes chromatin accessibility for cell type-specific master transcription factors [gene expression]
Cell type-specific master transcription factors (MTFs) play vital roles in defining cell identity and function. However, the roles ubiquitous factors play in the specification of cell identity remain underappreciated. Here we show that all three subunits of the ubiquitous heterotrimeric CCAAT-bindin...
ORGANISM(S): Mus musculus 
2014-08-14 | E-GEOD-56838 | biostudies-arrayexpress
ProteomicsThe exercise-regulated skeletal muscle phosphoproteome
Four healthy male volunteers (age: 24 - 27; BMI: 24.2 - 25.9 kg/m2) underwent a single bout of high-intensity bicycle exercise reaching a VO2 max approximately 95% with blood samples and muscle biopsies taken immediately pre- and post-exercise. Subjects reached 95% VO2 max in approximately 9 to 12 m...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080777 | MassIVE
TranscriptomicsISL1, a Regulator of Adipocyte Differentiation of Potential Importance in Visceral Fat
Visceral fat (VF) and subcutaneous fat (SF) are developmentally different tissues with different gene expression. Islet-1 (ISL1), a LIM-homeobox transcription factor with important developmental and regulatory function in islet, neural, and cardiac tissue, is virtually absent in SF but substantially...
ORGANISM(S): Mus musculus 
2012-09-05 | E-GEOD-40565 | biostudies-arrayexpress
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