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MetabolomicsVisceral obesity-Induced METTL27 regulation of the FABP5/PPARD/CPT1A axis in promoting colorectal cancer progression

The incidence of obesity and colorectal cancer (CRC) is rising annually. Obesity, particularly visceral obesity, poses a serious health threat, yet the association of obesity with CRC progression, as well as the role of visceral obesity, remains debated. This study analyzed 394 CRC patients ...

2025-10-06 | MTBLS13095 | MetaboLights
ProteomicsLung tissue proteomic of Cynomolgus Macaques before and after exposure to SARS-CoV-2
In this study, we established the COVID-19 infection model in cynomolgus macaques (CMs), the differentially expressed proteins was analyzed in lung tissue collected from 3 untreated (NC1-3) and 4 CMs inoculated with SARS-CoV-2 for 7 days (nCoV1-4). The results showed the differentially expressed gen...
ORGANISM(S): Macaca mulatta (Rhesus macaque) 
2022-07-06 | PXD034589 | Pride
Cynomolgus macaques Sars-cov-2 Lung tissue 
MetabolomicsComparison of Chemical Compositions in Pseudostellariae Radix from Different Cultivated Fields and Germplasms by NMR-Based Metabolomics
Pseudostellariae Radix (PR) is an important traditional Chinese medicine (TCM), which is consumed commonly for its positive health effects. However, the chemical differences of PR from different cultivated fields and germplasms are still unknown. In order to comprehensively compare the chemical comp...
2018-01-25 | MTBLS399 | MetaboLights
ProteomicsEndoplasmic Reticulum Stress-induced Histone Lactylation Mediating Immune Escape of Gastric Cancer via PDIA6 Overexpression in Dendritic Cells
First, cell histones were extracted using a histone extraction kit (Solarbio, China), followed by the preparation of protein samples. Protein samples were then isolated by SDS-PAGE and stained with Richfast SDS-PAGE Staining Buffer (Prosperich, China). The colloids were cut for MS analysis to determ...
ORGANISM(S): Mus <genus> 
2025-12-30 | PXD072553 |
ProteomicsThe interactional proteins with TANGO6 in U251 cells
To investigate the interactional proteins with TANGO6, we conducted MS.
ORGANISM(S): Homo Sapiens 
2024-02-04 | PXD049158 |
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