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Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermediates. The effects on...

2024-05-22 | MTBLS2347 | MetaboLights
Background: Mechanical forces play a crucial role in regulating cellular communication during tissue repair, yet how mechanical stimulation modulates endothelial exosome secretion and their effects on fibroblast activation remains unclear. Methods: In this study, endothelial cells were incorporated ...
ORGANISM(S): Homo Sapiens 
2025-12-25 | PXD072415 |
The nanoLC-MS/MS experiments were performed on a Q Exactive mass spectrometer (Thermo Scientific) in data-dependent mode, which allowed MS data acquisition at a high resolution of 70,000 (m/z 200) across an m/z range of 300–1600. The raw data from Q Exactive analysis were analyzed with Proteome Disc...
ORGANISM(S): Homo Sapiens 
2023-03-27 | PXD041140 |
Animal growth curves can provide essential information for animal breeders to optimize feeding and management strategies. However, the genetic mechanism underlying the phenotypic differentiation between the inflection point and asymptotic stages of the growth curve is not well characterized. Here, w...
ORGANISM(S): Sus scrofa 
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