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The identified stromal factors SDF1alpha, sFRP1 and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells. Human embryonic stem cell (hESC)-derived dopaminergic (DA) neurons are potentially useful for treating Parkinson’s disease (PD) through cell replacement therapy. Gen...
ORGANISM(S): Mus musculus 
The COVID-19 pandemic has become a world-wide health crisis. So far, most studies have focused on the epidemiology and pathogenesis of this infectious disease. Little attention has been paid to the disease sequelae in patients recovering from COVID-19, and nothing is known about the mechanisms under...
ORGANISM(S): Homo Sapiens 
2020-12-24 | PXD023305 |
HLA-DR molecules are highly expressed in synovial tissue (ST), the target of the immune response in chronic inflammatory arthritides, including in rheumatoid arthritis (RA) and Lyme arthritis (LA). In the current study, we identified HLA-DR-presented self-peptides (T cell epitopes) in ST, synovial f...
ORGANISM(S): Homo sapiens (Human) 
2016-10-13 | PXD003051 | Pride
effect of over-expression LIGHT on T cells for the liver gene expression; We used microarrays to detail the global programme of gene expression underlying WT and LIGHT Tg liver Experiment Overall Design: mice were selected at 4-8 wks old after 2 weeks HFD feeding for RNA extraction and hybridization...
ORGANISM(S): Mus musculus 
Advances in pluripotent stem cell and reprogramming technologies have given hope of generating hematopoietic stem cells (HSC) in culture. To succeed, greater understanding of the self-renewing HSC during human development is required. We discovered that glycophosphatidylinositol-anchored surface pro...
ORGANISM(S): Homo sapiens 
Advances in pluripotent stem cell and reprogramming technologies have given hope of generating hematopoietic stem cells (HSC) in culture. To succeed, greater understanding of the self-renewing HSC during human development is required. We discovered that glycophosphatidylinositol-anchored surface pro...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
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