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UnknownIncidence of healthcare-associated infections in a tertiary hospital in Beijing, China: results from a real-time surveillance system.

Background

To quantify the five year incidence trend of all healthcare-associated infections (HAI) using a real-time HAI electronic surveillance system in a tertiary hospital in Beijing, China.

Methods

The real-time surveillance system scans the hospital's electronic databases related...
S-EPMC6712817 | biostudies-literature
UnknownMiR-9a-5p regulates proliferation and migration of hepatic stellate cells under pressure through inhibition of Sirt1.

Aim

To reveal the functions of microRNAs (miRNAs) with respect to hepatic stellate cells (HSCs) in response to portal hypertension.

Methods

Primary rat HSCs were exposed to static water pressure (10 mmHg, 1 h) and the pressure-induced miRNA expression profile was detected by next-gene...
S-EPMC4566383 | biostudies-literature
UnknownOrdered clustering of single atomic Te vacancies in atomically thin PtTe2 promotes hydrogen evolution catalysis.
Exposing and stabilizing undercoordinated platinum (Pt) sites and therefore optimizing their adsorption to reactive intermediates offers a desirable strategy to develop highly efficient Pt-based electrocatalysts. However, preparation of atomically controllable Pt-based model catalysts to understand ...
S-EPMC8060321 | biostudies-literature
UnknownAtomically precise Ni clusters inducing active NiN<sub>2</sub> sites with uniform-large vacancies towards efficient CO<sub>2</sub>-to-CO conversion.
CO2 electroreduction to CO promises to give an efficient strategy for CO2 fixation and transformation. However, current reported active sites fail to deliver sufficient activity with high CO Faradic efficiency (FEco) over a wide range of potential. Here, we show a general synth...
S-EPMC12015452 | biostudies-literature
UnknownCharacterization of the Key Aroma Compounds in Three Truffle Varieties from China by Flavoromics Approach.
The volatile compounds of three different fresh-picked truffle varieties (Tuber sinensis, T1, Tuber sinoalbidum, T2 and Tuber sinoexcavatum, T3) were extracted by headspace solid-phase microextraction (HS-SPME). Separation and identification of volatile components and sulfur compounds were investiga...
S-EPMC6767217 | biostudies-literature
UnknownThe validity of neoadjuvant chemotherapy with paclitaxel plus S-1 is not inferior to that of SOX regimen for locally advanced gastric cancer: an observational study.

Background

Paclitaxel plus S-1(PTXS) has shown definite efficacy for advanced gastric cancer. However, the efficacy and safety of this regimen in neoadjuvant setting for locally advanced gastric cancer (LAGC) are unclear. This study aimed to compare the efficacy of neoadjuvant chemotherapy (...
S-EPMC9703660 | biostudies-literature
UnknownPro-thrombotic changes associated with exposure to ambient ultrafine particles in patients with chronic obstructive pulmonary disease: roles of lipid peroxidation and systemic inflammation.

Background

Exposure to particulate matter air pollution is associated with an increased risk of cardiovascular mortality in patients with chronic obstructive pulmonary disease (COPD), but the underlying mechanisms are not yet understood. Enhanced platelet and pro-thrombotic activity in COPD ...
S-EPMC9590143 | biostudies-literature
UnknownAxon-like aligned conductive CNT/GelMA hydrogel fibers combined with electrical stimulation for spinal cord injury recovery.
Rehabilitation and regenerative medicine are two promising approaches for spinal cord injury (SCI) recovery, but their combination has been limited. Conductive biomaterials could bridge regenerative scaffolds with electrical stimulation by inducing axon regeneration and supporting physiological elec...
S-EPMC10897856 | biostudies-literature
UnknownThe trans-ancestral genomic architecture of glycemic traits.
Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health. To date, most genetic studies of glycemic traits have focused on individuals of European ancestry. Here we aggregated genome-wide association studies comprising up to 281,416 individuals without diabetes (30...
S-EPMC7610958 | biostudies-literature
UnknownEfficient bi-allelic gene knockout and site-specific knock-in mediated by TALENs in pigs.
Pigs are ideal organ donors for xenotransplantation and an excellent model for studying human diseases, such as neurodegenerative disease. Transcription activator-like effector nucleases (TALENs) are used widely for gene targeting in various model animals. Here, we developed a strategy using TALENs ...
S-EPMC4220281 | biostudies-literature
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