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GenomicsMediation of CTCF transcriptional insulation by DEAD-box RNA-binding protein p68 and steroid receptor RNA activator SRA
CCCTC-binding factor (CTCF) is a DNA-binding protein that plays important roles in chromatin organization, though the mechanism by which CTCF carries out these functions is not fully understood. Recent studies show that CTCF recruits the cohesin complex to insulator sites and that cohesin is require...
ORGANISM(S): Homo sapiens 
2010-11-16 | E-GEOD-24126 | biostudies-arrayexpress
TranscriptomicsStromal factors SDF1alpha, sFRP1 and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells
The identified stromal factors SDF1alpha, sFRP1 and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells. Human embryonic stem cell (hESC)-derived dopaminergic (DA) neurons are potentially useful for treating Parkinson’s disease (PD) through cell replacement therapy. Gen...
ORGANISM(S): Mus musculus 
2012-06-24 | E-GEOD-20503 | biostudies-arrayexpress
Genomicsuk10k_rare_neuromuscular_rel_2012_11_27-sc-20121218 - samples
UK10K_RARE_NEUROMUSCULAR REL-2012-11-27
EGAD00001000298 | EGA
Genomicsuk10k_rare_neuromuscular_rel_2012_01_13-sc-20120611 - samples
UK10K_RARE_NEUROMUSCULAR REL-2012-01-13
EGAD00001000180 | EGA
Genomicsuk10k_rare_nmwg-rel-2013-03-06-sc-20140327 - samples
UK10K_RARE_NMWG REL-2013-03-06
EGAD00001000804 | EGA
Genomicsuk10k_rare_neuromuscular_rel_2013_04_20-sc-20130522 - samples
UK10K_RARE_NEUROMUSCULAR REL-2013-04-20
EGAD00001000418 | EGA
Genomicsuk10k_rare_neuromuscular_rel_2012_02_22-sc-20120613 - samples
UK10K_RARE_NEUROMUSCULAR REL-2012-02-22
EGAD00001000189 | EGA
Genomicsuk10k_rare_nmwg-rel-2013-09-09-sc-20140303 - samples
UK10K_RARE_NMWG REL-2013-09-09
EGAD00001000754 | EGA
Genomicsuk10k_rare_neuromuscular_rel_2012_07_05-sc-20120813 - samples
UK10K_RARE_NEUROMUSCULAR REL-2012-07-05
EGAD00001000219 | EGA
GenomicsUK10K RARE NEUROMUSCULAR
In the UK10K project we propose a series of complementary genetic approaches to find new low frequency/rare variants contributing to disease phenotypes. These will be based on obtaining the genome wide sequence of 4000 samples from the TwinsUK and ALSPAC cohorts (at 6x sequence coverage), and the ex...
EGAS00001000101 | EGA
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