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TranscriptomicsRNA-seq analysis of crypt samples isolated from the small intestine of Bach2 KO and control mice
Epithelial regeneration is critical for barrier maintenance and organ function after intestinal injury. Here, we found that Bach2 deficiency promotes the intestinal epithelial cell proliferation during homeostasis and facilitates the crypt regeneration after irradiation, resulting in a reduction of ...
ORGANISM(S): Mus musculus 
2021-01-12 | E-MTAB-9865 | biostudies-arrayexpress
ProteomicsThe differential proteins in dairy cow placental trophoblast cells-derived exosomes between P4 treatment and non P4 treatment
Inadequate fetomaternal interactions could directly lead to pregnancy failure in dairy cows. Exosomes are widely involved in endometrial matrix remodeling, immune function changes, placental development, and other processes of embryo implantation and pregnancy in dairy cows. However, the role of e...
ORGANISM(S): Bos Taurus 
2021-12-21 | PXD030586 |
ProteomicsPhosphoproteomics attributes aberrant signaling events to a druggable kinome in hepatocellular carcinom
To connect aberrant phospho-signaling events to therapeutic vulnerabilities in hepatocellular carcinoma (HCC), we performed a mass-spectrometry-based phosphoproteomic quantification of human HCC tumors, adjacent tissues and cell lines. We developed an integrated pipeline as the inference of druggabl...
ORGANISM(S): Homo Sapiens 
2023-01-02 | PXD023840 |
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