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ProteomicsProteogenomic Characterization of Skull-base Chordoma
Skull-base chordoma (SBC) is a rare, aggressive bone cancer with a high recurrent rate. Genomic studies of SBC have improved our understanding of the disease’s biology. However, the molecular biological characteristics and the effective therapy of SBC remain unknown. Here, we carried out an integrat...
ORGANISM(S): Homo Sapiens 
PXD053550 |
ProteomicsIntegrated Proteogenomic Characterization across Major Histological Types of Pituitary Neuroendocrine Tumors
Pituitary neuroendocrine tumor (PitNET) is one of the most common intracranial tumors. Due to its extensive tumor heterogeneity and the lack of high-quality tissues for biomarker discovery, the causative molecular mechanisms are far from being fully defined. Therefore, more studies are needed to imp...
ORGANISM(S): Homo Sapiens 
2022-10-17 | PXD031467 |
ProteomicsQuartet Protein Reference Materials for Multi-platform Assessment of Label-free Proteomics
We developed the Quartet as a bulk of proteome reference materials with built-in truth, and distributed the same aliquots to 15 laboratories in six cities of China with nine conventional LC-MS/MS platforms. Relative protein abundances from over 12,000 proteins on 816 MS files were obtained and compa...
ORGANISM(S): Homo Sapiens 
PXD043262 |
ProteomicsProteogenomics of urothelial bladder cancer progression reveals the distinguished molecular features of different pathological subtypes
We reported a comprehensive proteogenomics analysis, including whole-genome sequencing, RNA sequencing, and proteomics and phosphoproteomics profiling, of 448 trace-tumor-samples from 190 urothelial bladder neoplasm patients, covering the whole spectrum of disease stages and grades. DNA damage was a...
ORGANISM(S): Homo Sapiens 
2023-08-02 | PXD043775 |
ProteomicsValidation experiment for pan-sarcoma
the data of validation experiments for pan-sarcoma projects
ORGANISM(S): Homo Sapiens 
2024-01-03 | PXD047429 |
ProteomicsProteomics and phosphoproteomics of pan-sarcoma
we establish a 272 Chinese STS patients cohort containing 12 sarcoma subtypes, well-differentiated liposarcoma (WDLPS), myxoid liposarcoma (MLPS), dedifferentiated liposarcoma (DDLPS), angiosarcoma (AS), undifferentiated sarcoma (UPS), myxofibrosarcoma (MFS), other fibroblastic/myofibroblastic tumor...
ORGANISM(S): Homo Sapiens 
2024-01-03 | PXD047297 |
ProteomicsPlasma proteomic profiling discovers molecular features associated with upper urinary tract urothelial carcinoma
Upper tract urothelial carcinoma (UTUC) is often diagnosed late and exhibits poor prognosis. Only limited data are available concerning potential noninvasive biomarkers for disease monitoring. Here, we investigated the proteomic profile of plasma in 362 UTUC patients and 239 healthy control samples....
ORGANISM(S): Homo Sapiens 
2023-07-12 | PXD043774 |
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